Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759054 | 0.92 | HINT1 (0.54) | HINT1HPGDGSK3ARPS6KA3MAPK14 | |
| SCHEMBL7257443 | 0.92 | HINT1 (0.54) | HINT1HPGDGSK3ARPS6KA3MAPK14 | |
| SCHEMBL30612754 | 0.89 | HPGD (0.54) | HINT1HPGDGSK3ARPS6KA3MAPK14 | |
| SCHEMBL31583575 | 0.87 | FUT5 (0.53) | HINT1HPGDNT5EFUT5HPRT1 | |
| SCHEMBL20833471 | 0.86 | HPGD (0.51) | HINT1HPGDGSK3ARPS6KA3MAPK14 | |
| SCHEMBL7253951 | 0.85 | TYMP (0.49) | HINT1HPGDGSK3ARPS6KA3MAPK14 | |
| SCHEMBL7253950 | 0.85 | TYMP (0.49) | HINT1HPGDGSK3ARPS6KA3MAPK14 | |
| SCHEMBL18521008 | 0.84 | FUT5 (0.55) | HINT1HPGDGSK3ARPS6KA3MAPK14 | |
| SCHEMBL19242512 | 0.84 | HPGD (0.52) | HINT1HPGDNT5EFUT5TLR7 | |
| SCHEMBL19882058 | 0.84 | HPGD (0.52) | HINT1HPGDNT5EFUT5TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |