Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.49 |
| ▸ | HINT1 | P49773 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612754 | 0.91 | HPGD (0.54) | HPGDHPRT1HINT1NT5EFUT5 | |
| SCHEMBL18158915 | 0.89 | NT5E (0.53) | HPRT1HINT1NT5EFUT5POLB | |
| SCHEMBL31583575 | 0.88 | FUT5 (0.53) | HPGDHPRT1HINT1NT5EFUT5 | |
| SCHEMBL18158965 | 0.88 | NT5E (0.51) | HPRT1HINT1NT5EFUT5POLB | |
| SCHEMBL18521008 | 0.87 | FUT5 (0.55) | HPGDHPRT1HINT1NT5EFUT5 | |
| SCHEMBL25711923 | 0.86 | HINT1 (0.50) | HPGDHPRT1HINT1NT5EFUT5 | |
| SCHEMBL21539254 | 0.84 | FUT5 (0.50) | HPGDHPRT1HINT1NT5EFUT5 | |
| SCHEMBL21562192 | 0.83 | HPGD (0.52) | HPGDHPRT1HINT1NT5EFUT5 | |
| SCHEMBL19882058 | 0.83 | HPGD (0.52) | HPGDHPRT1HINT1NT5EFUT5 | |
| SCHEMBL20059041 | 0.83 | HPGD (0.52) | HPGDHPRT1HINT1NT5EFUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019053659-A1 | MODIFIED NUCLEOSIDE PHOSPHORAMIDITES | ALIOS BIOPHARMA, INC. (US) | 2019-03-21 | — | — | WO | disclosed |