Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16024745 | 0.85 | ERN1 (0.46) | ERN1TNKS2PTPN1KDM4EALDH1A1 | |
| SCHEMBL890444 | 0.85 | ERN1 (0.49) | ERN1TNKS2PTPN1KDM4EALDH1A1 | |
| SCHEMBL18525393 | 0.82 | ERN1 (0.46) | ERN1TNKS2PTPN1KDM4EALDH1A1 | |
| SCHEMBL18550567 | 0.81 | MAPT (0.47) | ERN1KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL18643742 | 0.80 | ERN1 (0.41) | ERN1TNKS2PTPN1KDM4EALDH1A1 | |
| SCHEMBL7520392 | 0.80 | ERN1 (0.57) | ERN1TNKS2PTPN1KDM4EALDH1A1 | |
| SCHEMBL18535615 | 0.80 | ERN1 (0.44) | ERN1TNKS2PTPN1KDM4EALDH1A1 | |
| SCHEMBL16014627 | 0.79 | ACHE (0.48) | ERN1TNKS2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL18541268 | 0.78 | TNKS2 (0.32) | TNKS2KDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL16024740 | 0.78 | G6PD (0.41) | ERN1TNKS2PTPN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131607-B2 | Process for preparing unsymmetric OCO pincer ligands from the group of the M-terphenyl compounds | EVONIK DEGUSSA GMBH (DE) | 2018-11-20 | — | — | US | disclosed |
| EP-3293189-B1 | PHOSPHITES WITH A DIHYDROXYTERPHENYL AND TWO PHENOLS | EVONIK DEGUSSA GMBH (DE) | 2018-11-14 | — | — | EP | disclosed |
| EP-3293192-B1 | PHOSPHITES WITH A DIHYDROXYTERPHENYL WITH A TETRAPHENYL DIOXAPHOSPHOLANE | EVONIK DEGUSSA GMBH (DE) | 2018-11-14 | — | — | EP | disclosed |
| EP-3293189-A1 | PHOSPHITES WITH A DIHYDROXYTERPHENYL AND TWO PHENOLS | Evonik Degussa GmbH (DE) | 2018-03-14 | — | — | EP | disclosed |
| EP-3293192-A1 | PHOSPHITES WITH A DIHYDROXYTERPHENYL WITH A TETRAPHENYL DIOXAPHOSPHOLANE | Evonik Degussa GmbH (DE) | 2018-03-14 | — | — | EP | disclosed |
| EP-3293191-A1 | PHOSPHITES WITH A DIHYDROXYTERPHENYL | Evonik Degussa GmbH (DE) | 2018-03-14 | — | — | EP | disclosed |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| EP-3133189-A1 | METHOD FOR THE PREPARATION OF ASYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF M TERPHENYL COMPOUNDS | Evonik Degussa GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
| EP-3133189-A1 | METHOD FOR THE PREPARATION OF ASYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF M TERPHENYL COMPOUNDS | Evonik Degussa GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131607-B2 | Process for preparing unsymmetric OCO pincer ligands from the group of the M-terphenyl compounds | COMT, MSMO1, TYR | ERN1 4109/4885TNKS2 1049/4885PTPN1 517/4885 |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | COMT, MSMO1, TYR | ERN1 4109/4885TNKS2 1049/4885PTPN1 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.