Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3204669 | 0.95 | GPR52 (0.49) | GPR52MAPTMEN1KMT2AS1PR4 | |
| SCHEMBL1851846 | 0.90 | GPR52 (0.45) | GPR52MAPTMEN1KMT2AS1PR4 | |
| SCHEMBL3211192 | 0.86 | GPR52 (0.47) | GPR52MAPTMEN1KMT2AS1PR4 | |
| SCHEMBL1853719 | 0.83 | GPR52 (0.44) | GPR52MAPTMEN1KMT2AS1PR4 | |
| SCHEMBL3198656 | 0.82 | GPR52 (0.49) | GPR52MEN1KMT2AS1PR4S1PR5 | |
| SCHEMBL3219110 | 0.81 | GPR52 (0.51) | GPR52S1PR4S1PR5SCDCES2 | |
| SCHEMBL1850452 | 0.80 | GPR52 (0.46) | GPR52MAPTS1PR4S1PR5SCD | |
| SCHEMBL1853390 | 0.80 | PNMT (0.43) | MAPTMEN1KMT2ASCDALDH1A1 | |
| SCHEMBL3218871 | 0.79 | GPR52 (0.71) | GPR52S1PR4S1PR5SCDALDH1A1 | |
| SCHEMBL1850455 | 0.78 | GPR52 (0.49) | GPR52MEN1KMT2AS1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |