Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354121 | 0.94 | MAPT (0.40) | KMT2APOLBL3MBTL1G6PDMAPT | |
| SCHEMBL18525567 | 0.92 | PKM (0.37) | KMT2APOLBL3MBTL1G6PDMAPT | |
| SCHEMBL18489497 | 0.82 | HPGD (0.41) | KMT2APOLBL3MBTL1G6PDMAPT | |
| SCHEMBL23644530 | 0.82 | HPGD (0.41) | KMT2APOLBL3MBTL1G6PDMAPT | |
| SCHEMBL469486 | 0.81 | KMT2A (0.46) | KMT2APOLBL3MBTL1MAPTTHRB | |
| SCHEMBL30933094 | 0.79 | KMT2A (0.60) | KMT2APOLBL3MBTL1MAPTCYP1A2 | |
| SCHEMBL10182675 | 0.79 | ALDH1A1 (0.59) | KMT2APOLBL3MBTL1MAPTALOX15 | |
| SCHEMBL18489492 | 0.79 | ALDH1A1 (0.47) | KMT2APOLBL3MBTL1MAPTCYP1A2 | |
| SCHEMBL18489491 | 0.79 | ALDH1A1 (0.47) | KMT2APOLBL3MBTL1MAPTCYP1A2 | |
| SCHEMBL12379905 | 0.77 | AMY1A (0.43) | KMT2APOLBL3MBTL1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186902-A1 | CATALYSTS | QATAR FOUNDATION (QA) | 2018-07-05 | — | — | US | disclosed |
| US-20180186902-A1 | CATALYSTS | QATAR FOUNDATION (QA) | 2018-07-05 | — | — | US | disclosed |
| WO-2017025701-A1 | CATALYSTS | QATAR FOUNDATION (QA) | 2017-02-16 | — | — | WO | disclosed |