Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18489585 | 0.80 | KDM4E (0.58) | GAAMAPTKMT2APOLBLMNA | |
| SCHEMBL18489587 | 0.80 | KDM4E (0.58) | GAAMAPTKMT2APOLBLMNA | |
| SCHEMBL18489492 | 0.79 | ALDH1A1 (0.47) | MAPTHTTKMT2APOLBLMNA | |
| SCHEMBL18489491 | 0.79 | ALDH1A1 (0.47) | MAPTHTTKMT2APOLBLMNA | |
| SCHEMBL18525565 | 0.77 | KMT2A (0.42) | GAAMAPTKMT2APOLBLMNA | |
| SCHEMBL18489473 | 0.77 | DHODH (0.48) | GAAMAPTHTTKMT2ALMNA | |
| SCHEMBL18489474 | 0.77 | DHODH (0.48) | GAAMAPTHTTKMT2ALMNA | |
| SCHEMBL18489487 | 0.76 | ALDH1A1 (0.50) | GAAMAPTHTTKMT2ALMNA | |
| SCHEMBL18489488 | 0.76 | ALDH1A1 (0.50) | GAAMAPTHTTKMT2ALMNA | |
| SCHEMBL30933094 | 0.75 | KMT2A (0.60) | GAAMAPTHTTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998895-B2 | Catalysts for olefin polymerization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-08-16 | — | — | US | disclosed |
| US-7998895-B2 | Catalysts for olefin polymerization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-08-16 | — | — | US | disclosed |
| US-20100222531-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100029469-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100029469-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-02-04 | — | — | US | disclosed |
| US-7439314-B2 | Catalysts for olefin polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439314-B2 | Catalysts for olefin polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222531-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | PORCN, PUF60, CAD | AMY1A 2174/4885GAA 3973/4885MAPT 1503/4885 |
| US-20100029469-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | PORCN, PUF60, CAD | AMY1A 2174/4885GAA 3973/4885MAPT 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.