Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.42 |
| ▸ | ACACB | O00763 | 11/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13645890 | 0.81 | TAS1R3 (0.47) | MTNR1AMTNR1BACACBALDH1A1ACACA | |
| SCHEMBL2736111 | 0.79 | MTNR1A (0.43) | MTNR1AMTNR1BACACBALDH1A1ACACA | |
| SCHEMBL13242519 | 0.77 | GABRP (0.43) | MTNR1AMTNR1BACACBALDH1A1 | |
| SCHEMBL13932519 | 0.76 | — | — | |
| SCHEMBL7890560 | 0.76 | — | — | |
| SCHEMBL8142982 | 0.76 | — | — | |
| SCHEMBL8435514 | 0.76 | — | — | |
| SCHEMBL13452338 | 0.76 | — | — | |
| SCHEMBL18520329 | 0.76 | — | — | |
| SCHEMBL28663197 | 0.76 | MTNR1A (0.41) | MTNR1AMTNR1BACACBALDH1A1ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9575080-B2 | — | — | 2017-02-21 | — | — | US | disclosed |