Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRE | P78334 | 2/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 9/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149718 | 0.87 | ALDH1A1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28663197 | 0.84 | MTNR1A (0.41) | ACACBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28513362 | 0.82 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13452338 | 0.81 | — | — | |
| SCHEMBL13645890 | 0.81 | TAS1R3 (0.47) | ACACBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL18520329 | 0.81 | — | — | |
| SCHEMBL7890560 | 0.81 | — | — | |
| SCHEMBL27396612 | 0.81 | TAS1R3 (0.47) | ACACBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL2330613 | 0.81 | BHMT (0.46) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL22315077 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759435-B2 | Adducts and curable compositions using same | LOCTITE (R&D) LIMITED (IE) | 2010-07-20 | — | — | US | disclosed |
| US-20080076886-A1 | Backbones of polyethers, perfluorinated polyethers, polydimethylsiloxanes and hydroxy terminated polybutadienes coupled to phenyl, biphenyl, bisphenol A, bisphenol F, bisphenol S, bisphenol E, allyl, alkyl, alkenyl, carboxy, N-carbamoyl, cyclic amides, epoxy and a thermosetting component; toughening | LOCTITE (R&D) LIMITED | 2008-03-27 | — | — | US | disclosed |