Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185723 | 0.94 | KCNH2 (0.41) | KMT2AGAAMAPTALDH1A1KDM4E | |
| SCHEMBL185726 | 0.92 | GAA (0.42) | KMT2AGAALMNAMAPTRAB9A | |
| SCHEMBL186112 | 0.90 | HDAC1 (0.39) | MAPTRAB9AALDH1A1NPSR1MMP13 | |
| SCHEMBL2813652 | 0.87 | KMT2A (0.42) | KMT2AGAALMNAMAPTRAB9A | |
| SCHEMBL185869 | 0.87 | ALDH1A1 (0.35) | KMT2ALMNAMAPTRAB9AALDH1A1 | |
| SCHEMBL186396 | 0.85 | HPGD (0.40) | LMNAMAPTKDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL185629 | 0.81 | POLB (0.36) | KMT2AGAALMNARAB9AEPHX2 | |
| SCHEMBL2808159 | 0.81 | KCNH2 (0.43) | KMT2AGAAMAPTALDH1A1KDM4E | |
| SCHEMBL186209 | 0.80 | POLB (0.34) | KMT2AGAALMNAMAPTEPHX2 | |
| SCHEMBL205144 | 0.79 | CTDSP1 (0.32) | GAAMAPTALDH1A1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |