SCHEMBL1853322

SCHEMBL1853322

O=C(O)CNCC(O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.35
EGLN1 Q9GZT9 3/20 0.35
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
CTH P32929 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
PHF8 Q9UPP1 2/20 0.31
KDM2A Q9Y2K7 2/20 0.31
KDM7A Q6ZMT4 1/20 0.31
KDM4E B2RXH2 1/20 0.31
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
FOLH1 Q04609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2558809 0.79 HMGCR (0.40) LMNAEGLN1LDHASRRALKBH5
SCHEMBL15542883 0.79 LMNA (0.38) LMNAEGLN1LDHASRRALKBH5
SCHEMBL3964410 0.77 LDHA (0.30) LMNAEGLN1LDHASRRALKBH5
SCHEMBL5827218 0.76 LMNA (0.33) LMNAEGLN1LDHASRRALKBH5
SCHEMBL496333 0.76 EGLN1 (0.37) LMNAEGLN1LDHASRRALKBH5
SCHEMBL345581 0.76 EGLN1 (0.33) LMNAEGLN1LDHASRRALKBH5
SCHEMBL7571808 0.75 HMGCR (0.37) LMNAEGLN1CTHALDH1A1HMGCR
SCHEMBL27023 0.75
SCHEMBL4816014 0.75 LMNA (0.50) LMNAEGLN1LDHASRRALKBH5
Hydrochloric Acid SCHEMBL16057049 0.74 EGLN1 (0.32) LMNAEGLN1LDHASRRALKBH5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230414760-A1 PHARMACEUTICAL FORMULATION ASTRAZENECA UK LIMITED (GB) 2023-12-28 US claimed
EP-4243780-A1 PHARMACEUTICAL FORMULATION AstraZeneca UK Limited (GB) 2023-09-20 EP claimed
US-20230126528-A1 A LIBRARY OF PREFABRICATED MICROPARTICLES AND PRECURSORS THEREOF BLINK AG (DE) 2023-04-27 US claimed
EP-4078180-A1 A LIBRARY OF PREFABRICATED MICROPARTICLES AND PRECURSORS THEREOF Blink AG (DE) 2022-10-26 EP claimed
WO-2022101826-A1 PHARMACEUTICAL FORMULATION ASTRAZENECA UK LIMITED (GB) 2022-05-19 WO claimed
WO-2021122563-A1 A LIBRARY OF PREFABRICATED MICROPARTICLES AND PRECURSORS THEREOF BLINK AG (DE) 2021-06-24 WO claimed
EP-3839509-A1 A LIBRARY OF PREFABRICATED MICROPARTICLES AND PRECURSORS THEREOF Blink AG (DE) 2021-06-23 EP claimed
US-20170100337-A1 Naltrexone hydrochloride compositions PURDUE PHARMA LP (US) 2017-04-13 US claimed
CN-102301235-B Stabilized antibody compositions and methods for stabilizing same ABBVIE INC 2014-11-19 CN claimed
US-20130338245-A1 ISOLATION OF NUCLEIC ACIDS Life Technologies Corporation (US) 2013-12-19 US claimed
WO-2003077867-A2 NALTREXONE HYDROCHLORIDE COMPOSITIONS EURO-CELTIQUE, S.A. (LU) 2003-09-25 WO claimed
EP-1345952-A2 ISOLATION OF NUCLEIC ACIDS DNA Research Innovations Limited (GB) 2003-09-24 EP claimed
US-20030054395-A1 Isolation of nucleic acids Life Technologies Corporation 2003-03-20 US claimed
US-20030008320-A1 Isolation of nucleic acids Life Technologies Corporation 2003-01-09 US claimed
WO-2002048164-A2 ISOLATION OF NUCLEIC ACIDS DNA RESEARCH INNOVATIONS LIMITED (GB) 2002-06-20 WO claimed
US-20010018513-A1 Isolation of nucleic acids Life Technologies Corporation 2001-08-30 US claimed
EP-0527781-A4 METHODS AND FORMULATIONS FOR STABILIZING FIBROBLAST GROWTH FACTOR 1993-05-26 EP claimed
EP-0527781-A1 METHODS AND FORMULATIONS FOR STABILIZING FIBROBLAST GROWTH FACTOR SCIOS NOVA INC. (US) 1993-02-24 EP claimed
WO-1991015509-A1 METHODS AND FORMULATIONS FOR STABILIZING FIBROBLAST GROWTH FACTOR SCIOSNOVA INC. (US) 1991-10-17 WO claimed
US-4559291-A DIFFUSION TRANSFER ASSEMBLAGES USING REDOX DYE-RELEASERS, LIGUAND COMPETES FOR METAL TO METAL HYDROXIDE FORMATION EASTMAN KODAK COMPANY (US) 1985-12-17 US claimed