SCHEMBL3964410

SCHEMBL3964410

O=C(O)CNCC(O)(CO)CO

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.30
SRR Q9GZT4 1/20 0.30
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9053747 0.78 LDHA (0.32) LDHASRRLMNAALKBH5SUCNR1
SCHEMBL1853322 0.77 LMNA (0.35) LDHASRRLMNAALKBH5SUCNR1
SCHEMBL31000606 0.74 NAALAD2 (0.32) LMNAEGLN1
SCHEMBL2558809 0.73 HMGCR (0.40) LDHASRRLMNAALKBH5SUCNR1
SCHEMBL7039700 0.71 ALDH1A1 (0.48) LDHASRR
SCHEMBL345581 0.70 EGLN1 (0.33) LDHASRRLMNAALKBH5SUCNR1
SCHEMBL5827218 0.70 LMNA (0.33) LDHASRRLMNAALKBH5SUCNR1
SCHEMBL496333 0.70 EGLN1 (0.37) LDHASRRLMNAALKBH5SUCNR1
SCHEMBL66245 0.70
SCHEMBL7571808 0.70 HMGCR (0.37) LMNAEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536594-A 5-amino-2,3-dihydrothiazine-1,4-dione crystal 麦翠奥制药公司 2022-12-30 CN disclosed
CN-109071461-B Method for preparing 5-amino-2, 3-dihydrophthalazine-1, 4-diketone crystal 麦翠奥制药公司 2022-06-21 CN disclosed
CN-109563052-A 5-amino-2, 3-dihydrothiazine-1, 4-dione crystals 麦翠奥制药公司 2019-04-02 CN disclosed
CN-109071461-A The method for preparing 5- amino -2,3- dihydro thiazine -1,4- diketone crystalline solid 麦翠奥制药公司 2018-12-21 CN disclosed
WO-2009040085-A2 USE OF EXENDIN-4 AND OPTIONALLY SALUSIN-ALPHA AS THERAPEUTIC AGENT(S) MONDOBIOTECH LABORATORIES AG (LI) 2009-04-02 WO disclosed
EP-1150985-B1 A REAGENT SYSTEM AND METHOD FOR INCREASING THE LUMINESCENCE OF LANTHANIDE(III) MACROCYCLIC COMPLEXES LEIF ROBERT C (US) 2004-06-30 EP disclosed
US-6750005-B2 MIXTURE CONTAINING SURFACTANTS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-06-15 US disclosed
US-20020132992-A1 Reagent system and method for increasing the luminescence of lanthanide(III) macrocyclic complexes NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-09-19 US disclosed
EP-1150985-A4 A REAGENT SYSTEM AND METHOD FOR INCREASING THE LUMINESCENCE OF LANTHANIDE(III) MACROCYCLIC COMPLEXES LEIF ROBERT C (US) 2002-03-20 EP disclosed
US-6340744-B1 SPECTROFLUORIMETRICALLY DETECTION MACROCYCLIC COMPLEX NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-01-22 US disclosed
EP-1150985-A1 A REAGENT SYSTEM AND METHOD FOR INCREASING THE LUMINESCENCE OF LANTHANIDE(III) MACROCYCLIC COMPLEXES Leif, Robert C. (US) 2001-11-07 EP disclosed
WO-2000042048-A1 A REAGENT SYSTEM AND METHOD FOR INCREASING THE LUMINESCENCE OF LANTHANIDE(III) MACROCYCLIC COMPLEXES LEIF ROBERT C (US) 2000-07-20 WO disclosed