SCHEMBL18533503

SCHEMBL18533503

CCC(CCCCCN)C(CC)CCCCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
KMT2A Q03164 3/20 0.63
LMNA P02545 2/20 0.63
THRB P10828 2/20 0.63
MEN1 O00255 2/20 0.63
ALOX15 P16050 2/20 0.63
PLG P00747 1/20 0.63
SLC6A2 P23975 1/20 0.63
RECQL P46063 1/20 0.63
SLC6A3 Q01959 1/20 0.63
CYP2D6 P10635 1/20 0.59
NFKB1 P19838 1/20 0.59
BLM P54132 2/20 0.57
NPSR1 Q6W5P4 2/20 0.57
HDAC11 Q96DB2 6/20 0.50
TSHR P16473 5/20 0.50
FFAR4 Q5NUL3 2/20 0.50
FFAR1 O14842 2/20 0.50
GABRR3 A8MPY1 1/20 0.50
GABRP O00591 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2936745 0.90 ALDH1A1 (0.62) ALDH1A1KMT2ALMNAMEN1ALOX15
SCHEMBL7034531 0.85 ALDH1A1 (0.67) ALDH1A1KMT2ALMNAMEN1ALOX15
SCHEMBL5879118 0.85 FFAR4 (0.69) ALDH1A1KMT2ALMNAMEN1ALOX15
SCHEMBL14359961 0.84 ALDH1A1 (0.55) ALDH1A1KMT2ALMNAMEN1ALOX15
SCHEMBL18869135 0.83 NFKB1 (0.61) ALDH1A1KMT2ALMNATHRBMEN1
SCHEMBL14360303 0.83 ALDH1A1 (0.55) ALDH1A1KMT2ALMNAMEN1ALOX15
SCHEMBL9618680 0.82 LMNA (0.71) ALDH1A1KMT2ALMNATHRBMEN1
SCHEMBL14360113 0.82 ALDH1A1 (0.50) ALDH1A1KMT2ALMNAMEN1ALOX15
Sebacic Acid SCHEMBL9501168 0.79 LMNA (1.00) ALDH1A1KMT2ALMNATHRBMEN1
12-Aminododecanoic Acid SCHEMBL20767098 0.79 LMNA (1.00) ALDH1A1KMT2ALMNATHRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231194-B1 FOLATE-IRNA CONJUGATES ALNYLAM PHARMACEUTICALS INC (US) 2017-02-22 EP disclosed