SCHEMBL18534019

SCHEMBL18534019

Cc1ccc2c(c1F)CC(C)C2

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.31
BRD4 O60885 1/20 0.30
CREBBP Q92793 1/20 0.30
PTPN1 P18031 1/20 0.30
DRD2 P14416 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12433438 0.83 CYP2A6 (0.42) DRD2DRD3
SCHEMBL410138 0.79 HTR2C (0.37) ACHEBRD4CREBBPPTPN1
SCHEMBL18220725 0.78 DRD2 (0.36) DRD2DRD3
SCHEMBL21386527 0.76
SCHEMBL21531778 0.76 ACHE (0.31) ACHEBRD4CREBBPPTPN1
SCHEMBL16316899 0.76 ACHE (0.31) ACHEBRD4CREBBPPTPN1
SCHEMBL10284502 0.76 DRD2 (0.33) DRD2DRD3
SCHEMBL7156116 0.75 ACHE (0.40) ACHE
SCHEMBL16233590 0.71 DRD2 (0.52) BRD4CREBBPDRD2DRD3
SCHEMBL15864886 0.71 CHRNB2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3810724-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-11-22 EP disclosed
EP-4261269-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2023-10-18 EP disclosed
EP-3877484-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2023-09-13 EP disclosed
WO-2022128847-A1 DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
EP-3839009-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2021-06-23 EP disclosed
EP-3519533-B1 POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM MERCK PATENT GMBH (DE) 2020-12-16 EP disclosed
EP-3510122-B1 LIQUID-CRYSTAL MEDIA AND LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2020-12-16 EP disclosed
EP-3319964-B1 DITHIO-ALKYL-PYRROLO-PYRROLES AND USE THEREOF AS DYES MERCK PATENT GMBH (DE) 2020-07-22 EP disclosed
EP-3347435-B1 PRIVACY WINDOW MERCK PATENT GMBH (DE) 2020-04-15 EP disclosed
EP-3140369-B1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2019-10-23 EP disclosed
EP-3212734-B1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2019-05-15 EP disclosed
EP-3177694-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2019-01-02 EP disclosed
EP-3090033-B1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2018-07-04 EP disclosed
EP-2722380-B1 Liquid crystal medium, method for the stabilisation thereof and liquid crystal display MERCK PATENT GMBH (DE) 2018-02-21 EP disclosed
EP-2889357-B1 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2018-02-21 EP disclosed
EP-2855630-B1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2017-12-20 EP disclosed
EP-2855631-B1 MESOGENIC MEDIA AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2017-09-20 EP disclosed
EP-3049506-B1 COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-06-14 EP disclosed
EP-3044288-B1 MESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-05-17 EP disclosed
EP-3133137-A1 LIQUID CRYSTALLINE MEDIUM AND ELECTRO-OPTIC DISPLAY Merck Patent GmbH (DE) 2017-02-22 EP disclosed