SCHEMBL410138

SCHEMBL410138

Cc1ccc2c(c1C)CC(C)C2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.37
HTR2A P28223 2/20 0.37
HTR2B P41595 2/20 0.37
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALOX15 P16050 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KIF11 P52732 4/20 0.34
ADRA2A P08913 2/20 0.34
ADRA2B P18089 2/20 0.34
ADRA2C P18825 2/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ACHE P22303 1/20 0.32
STAT3 P40763 1/20 0.32
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21531778 0.79 ACHE (0.31) ACHEBRD4CREBBPPTPN1
SCHEMBL16316899 0.79 ACHE (0.31) ADRA2AADRA2BADRA2CACHEBRD4
SCHEMBL18534019 0.79 ACHE (0.31) ACHEBRD4CREBBPPTPN1
SCHEMBL7156116 0.78 ACHE (0.40) KDM4EMEN1KMT2AACHE
SCHEMBL8692015 0.77 ADRA1A (0.41) HTR2CHTR2AHTR2B
SCHEMBL24336721 0.72 HTR2A (0.36) HTR2CHTR2AHTR2B
SCHEMBL12433431 0.67 ALDH1A1 (0.39) KDM4EHSD17B10
SCHEMBL8689562 0.67 DRD3 (0.57) ALOX15
SCHEMBL23607799 0.67 MEN1 (0.33) HTR2CHTR2AHTR2BMEN1KMT2A
SCHEMBL24718000 0.67 ALDH1A1 (0.42) KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895789-B2 Fuel composition for use in gasoline engines SHELL OIL COMPANY (US) 2014-11-25 US claimed
US-8895789-B2 Fuel composition for use in gasoline engines SHELL OIL COMPANY (US) 2014-11-25 US disclosed
US-8876920-B2 Fuel composition for use in gasoline engines SHELL OIL COMPANY (US) 2014-11-04 US disclosed
EP-2367908-B1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES SHELL INT RESEARCH (NL) 2013-02-20 EP disclosed
US-20120101316-A1 METHOD FOR THE PREPARATION OF A FUEL COMPOSITION FOR USE IN GASOLINE ENGINES AND BLENDING COMPONENT SHELL OIL COMPANY 2012-04-26 US disclosed
US-20120022304-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES SHELL OIL COMPANY (US) 2012-01-26 US disclosed
EP-2367908-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES Shell Internationale Research Maatschappij B.V. (NL) 2011-09-28 EP disclosed
EP-2367906-A1 METHOD FOR THE PREPARATION OF A FUEL COMPOSITION FOR USE IN GASOLINE ENGINES AND BLENDING COMPONENT Shell Internationale Research Maatschappij B.V. (NL) 2011-09-28 EP disclosed
EP-2367907-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES Shell Internationale Research Maatschappij B.V. (NL) 2011-09-28 EP disclosed
WO-2010066879-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2010-06-17 WO disclosed
WO-2010066876-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2010-06-17 WO disclosed
WO-2010066881-A1 METHOD FOR THE PREPARATION OF A FUEL COMPOSITION FOR USE IN GASOLINE ENGINES AND BLENDING COMPONENT SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2010-06-17 WO disclosed