Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535661 | 0.86 | RAB9A (0.41) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL21116509 | 0.85 | RXFP1 (0.38) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL18535462 | 0.83 | KDM4E (0.38) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL18583698 | 0.83 | STS (0.48) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL18535472 | 0.81 | KDM4E (0.37) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL18535504 | 0.81 | TP53 (0.48) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL18535452 | 0.81 | MAOB (0.40) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL18535533 | 0.81 | NPC1 (0.46) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL24595652 | 0.79 | THRB (0.47) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL18583382 | 0.79 | STS (0.40) | NPC1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |
| EP-3133065-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |