Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18536568 | 0.86 | NPC1 (0.39) | ITGB1ITGA4ITGB3ITGAVITGA5 | |
| SCHEMBL18536535 | 0.69 | SIGMAR1 (0.33) | ITGB1ITGA4ITGB3ITGAVITGA5 | |
| SCHEMBL18536645 | 0.67 | ITGB1 (0.51) | ITGB1ITGA4ITGB3ITGAVITGA5 | |
| SCHEMBL13433106 | 0.64 | NPC1 (0.61) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL29340598 | 0.63 | ALDH1A1 (0.34) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL22184248 | 0.63 | ALDH1A1 (0.34) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL11125037 | 0.62 | HPGD (0.63) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL13479962 | 0.62 | TDP1 (0.63) | MEN1KMT2AKDM4EL3MBTL1TSHR | |
| SCHEMBL12139537 | 0.61 | NPC1 (0.57) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL24732254 | 0.60 | HPGD (0.55) | ITGB1ITGB3ITGAVITGA5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170860-B9 | BENZIMIDAZOLE DERIVATIVES | PFIZER (US) | 2017-02-22 | — | — | EP | disclosed |