SCHEMBL185367

SCHEMBL185367

[CH2]C(CC)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
MIF P14174 1/20 0.42
TAAR1 Q96RJ0 4/20 0.41
HTR2A P28223 3/20 0.41
HRH1 P35367 2/20 0.41
TRPA1 O75762 3/20 0.41
HKDC1 Q2TB90 1/20 0.41
AOC3 Q16853 1/20 0.39
NOS3 P29474 1/20 0.39
NOS2 P35228 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3899438 1.00 LMNA (0.52) LMNAMIFTAAR1HTR2AHRH1
SCHEMBL2343378 1.00 LMNA (0.52) LMNAMIFTAAR1HTR2AHRH1
SCHEMBL27508732 0.97 LMNA (0.50) LMNAMIFTAAR1HTR2AHRH1
SCHEMBL29000471 0.83 RXRA (0.42) LMNAHKDC1
SCHEMBL8603424 0.81 LTA4H (0.52) LMNA
SCHEMBL135231 0.80 AOC3 (0.46) LMNATAAR1HTR2AHRH1TRPA1
SCHEMBL27660368 0.78 AOC3 (0.44) LMNATAAR1HTR2AHRH1TRPA1
SCHEMBL1555621 0.78 UGT2B7 (0.52) AOC3MEN1KMT2A
SCHEMBL536902 0.77 POLB (0.45) LMNAHTR2AHRH1AOC3POLB
SCHEMBL16960887 0.77 ACHE (0.46) LMNATAAR1AOC3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2455 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207253-A1 Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2024-06-27 US claimed
US-20240188441-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE, AND THE CONDENSED CYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-06 US claimed
US-20230219884-A1 PREPARATION METHOD OF ACRYLONITRILE DIMER LG CHEM, LTD. (KR) 2023-07-13 US claimed
EP-4144721-A1 PREPARATION METHOD OF ACRYLONITRILE DIMER Lg Chem, Ltd. (KR) 2023-03-08 EP claimed
WO-2022245951-A1 INHIBITORS OF CDR1 FOR REVERSAL OF AZOLE DRUG RESISTANCE IN FUNGAL INFECTIONS UNM RAINFOREST INNOVATIONS (US) 2022-11-24 WO claimed
US-20190218219-A1 SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS INTRA-CELLULAR THERAPIES, INC. (US) 2019-07-18 US claimed
CN-106279256-A A kind of double [three (2 methyl 2 phenyl) propyl group stannum] 2,2 ' biphenyl dicarboxylic acid ester coordination compounds and preparation method and application 衡阳师范学院 2017-01-04 CN claimed
CN-101641226-B Rubber composition, method of making the same, and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2013-02-13 CN claimed
CN-1738829-B New 2',5'-oligoadenylic acid analog SANKYO CO 2012-11-28 CN claimed
CN-102382054-A Parazole and isoxazole derivative, preparation method for same and application thereof UNIV PLA 2ND MILITARY MEDICAL 2012-03-21 CN claimed
EP-0810212-A2 Organic peroxide stabilization with alpha-hydroxyalkyl peroxides WITCO CORPORATION (US) 1997-12-03 EP claimed
EP-0810213-A2 Organic peroxide stabilization with beta-dicarbonyl or cyclic alpha-diketone compounds WITCO CORPORATION (US) 1997-12-03 EP claimed
EP-0810211-A2 Organic peroxide stabilization with phosphomolybdic acid WITCO CORPORATION (US) 1997-12-03 EP claimed
CN-1163261-A Novel aspartyl amide derivative and sweetener AJINOMOTO GENERAL FOODS INC (JP) 1997-10-29 CN claimed
US-5654463-A Organic peroxide stabilization with α-hydroxyalkyl peroxides WITCO CORPORATION (US) 1997-08-05 US claimed
US-5654464-A RETARDING THE RATE OF DECOMPOSITION OF ESPECIALLY PEROXYDICARBONATE AND DIACYL PEROXIDE COMPOSITIONS; NONEXPLOSIVE; HEAT RESISTANCE; FREE RADICAL CATALYSTS; ADDITION POLYMERIZATION CATALYSTS WITCO CORPORATION (US) 1997-08-05 US claimed
EP-0784050-A1 Novel aspartylamide derivatives and sweeteners Ajinomoto Co., Inc. (JP) 1997-07-16 EP claimed
EP-0407137-B1 Benzazine compounds and pharmaceutical uses thereof YOSHITOMI PHARMACEUTICAL (JP) 1996-05-01 EP claimed
US-4038414-A ANTIARRHYTHMIA AGENTS CIBA-GEIGY CORPORATION (US) 1977-07-26 US claimed
US-4014920-A N-cinnamylcarbamic acid esters CIBA-GEIGY CORPORATION (US) 1977-03-29 US claimed