Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27303234 | 0.78 | HRH3 (0.50) | HRH3HRH4 | |
| SCHEMBL304176 | 0.77 | TDP1 (0.78) | KMT2A | |
| SCHEMBL18381285 | 0.76 | TBXAS1 (0.62) | HRH3HRH4 | |
| SCHEMBL13061496 | 0.76 | LTA4H (0.62) | — | |
| SCHEMBL713213 | 0.76 | LTA4H (0.62) | — | |
| Proxyfan SCHEMBL29462311 | 0.76 | HRH3 (0.87) | HRH3HRH4 | |
| SCHEMBL15875499 | 0.76 | L3MBTL1 (0.42) | HRH3HRH4MEN1KMT2A | |
| SCHEMBL304802 | 0.75 | TDP1 (0.60) | KMT2A | |
| Ammonia Solution, Strong SCHEMBL28588274 | 0.75 | TDP1 (0.75) | KMT2A | |
| Bicarbonate SCHEMBL7699565 | 0.75 | TDP1 (0.75) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943494-B1 | PYRIDO- OR PYRROLO-FUSED PYRIMIDINE DERIVATIVES AS AUTOTAXIN INHIBITORS FOR TREATING PAIN | LILLY CO ELI (US) | 2017-02-22 | — | — | EP | disclosed |