SCHEMBL18537263

SCHEMBL18537263

COc1ccc(C(C)(N)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 11/20 0.54
KCNH2 Q12809 1/20 0.54
CA4 P22748 1/20 0.52
LTA4H P09960 2/20 0.50
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
TRPA1 O75762 1/20 0.45
AOC3 Q16853 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28770177 1.00 KIF11 (0.54) KIF11KCNH2CA4LTA4HCA12
SCHEMBL7043985 0.91 CA1 (0.55) KIF11KCNH2CA4CA12CA1
SCHEMBL113271 0.85 KCNN4 (0.61) KIF11KCNH2CA4LTA4HCA12
Triphenylmethanamine SCHEMBL14120500 0.85 KCNN4 (0.61) KIF11KCNH2CA4LTA4HCA12
SCHEMBL1271654 0.85 KCNN4 (0.61) KIF11KCNH2CA4LTA4HCA12
Hydrochloric Acid SCHEMBL20241920 0.83 KCNN4 (0.58) KIF11KCNH2CA4LTA4HCA12
SCHEMBL2689280 0.83 CA4 (0.56) KIF11KCNH2CA4LTA4HCA12
SCHEMBL4570566 0.83 CA4 (0.56) KIF11KCNH2CA4LTA4HCA12
SCHEMBL25048 0.83 CA4 (0.56) KIF11KCNH2CA4LTA4HCA12
SCHEMBL10194078 0.82 ALDH1A1 (0.52) KIF11KCNH2AOC3SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110437230-B Tertiary amine compound, diphosphine ligand, intermediate and preparation method thereof 中国科学院上海有机化学研究所 2022-06-21 CN disclosed
EP-3133445-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL OSAKA UNIVERSITY (JP) 2017-02-22 EP disclosed