SCHEMBL25048

SCHEMBL25048

COc1ccc(C(C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.56
ESR1 P03372 2/20 0.56
ESR2 Q92731 2/20 0.56
LTA4H P09960 2/20 0.54
KIF11 P52732 7/20 0.53
KCNH2 Q12809 1/20 0.53
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
TRPA1 O75762 1/20 0.48
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
KMT2A Q03164 1/20 0.45
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4570566 1.00 CA4 (0.56) CA4ESR1ESR2LTA4HKIF11
SCHEMBL12459850 0.92 ACHE (0.58) CA4ESR1ESR2LTA4HKIF11
SCHEMBL3098811 0.91 CA1 (0.61) CA4LTA4HCA12CA1CA2
SCHEMBL24258459 0.90 ESR1 (0.47) CA4ESR1ESR2LTA4HKIF11
SCHEMBL16591527 0.90 ESR2 (0.74) CA4ESR1ESR2LTA4HKIF11
SCHEMBL20878780 0.90 ESR1 (0.47) CA4ESR1ESR2LTA4HKIF11
SCHEMBL18127940 0.87 CA4 (0.52) CA4ESR1ESR2LTA4HKIF11
SCHEMBL2689280 0.86 CA4 (0.56) CA4ESR1ESR2LTA4HKIF11
SCHEMBL15628358 0.86 KIF11 (0.43) CA4ESR1ESR2LTA4HKIF11
SCHEMBL13054813 0.86 KIF11 (0.46) CA4ESR1ESR2LTA4HKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710165-B Method for preparing 4,4' -dimethoxy trityl chloride by utilizing oligonucleotide synthesis waste liquid 北京擎科生物科技有限公司 2023-05-26 CN claimed
CN-115710165-A Method for preparing 4,4' -bis (methoxy) trityl chloride by using oligonucleotide synthesis waste liquid 北京擎科生物科技有限公司 2023-02-24 CN claimed
WO-2025137730-A1 N-SUBSTITUTED TRYPTAMINES AND N-SUBSTITUTED LYSERGAMIDES AND THEIR USE AS THERAPEUTIC AGENTS ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. (US) 2025-06-26 WO disclosed
US-12030911-B2 Synthesis and biological activity of phosphoramidimidate and phosphoramidate DNA THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2024-07-09 US disclosed
US-20240209017-A1 STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-06-27 US disclosed
WO-2024006477-A1 MULTIPLEX DYE COMPOUNDS Life Technologies Corporation (US) 2024-01-04 WO disclosed
US-11801306-B2 Compositions and methods for targeted RNA delivery VERVE THERAPEUTICS, INC. (US) 2023-10-31 US disclosed
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND AARHUS UNIVERSITET (DK) 2023-10-05 US disclosed
WO-2023186842-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES F. HOFFMANN-LA ROCHE AG (CH) 2023-10-05 WO disclosed
US-20230304932-A1 COMPOSITIONS, SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS INVOLVING ENERGY TRANSFER DYE CONJUGATES AND ANALYTES COMPRISING THE SAME Life Technologies Corporation 2023-09-28 US disclosed
US-20230304932-A1 COMPOSITIONS, SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS INVOLVING ENERGY TRANSFER DYE CONJUGATES AND ANALYTES COMPRISING THE SAME Life Technologies Corporation 2023-09-28 US disclosed
US-20070123713-A1 Polycyclic dihydroxy compound and methods for preparation CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-31 US disclosed
US-20070123682-A1 Polycarbonates, polyesters, polycarbonateesters, polyurethanes and epoxy resins prepared from monomers including N-4-[1,1'-di(p-hydroxyphenyl)ethyl]phenyl phthalimide or derivatives; articles with improved chemical resistance and high glass transition temperatures and refractive indices SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-05-31 US disclosed
US-20070082349-A1 Photocrosslinking probes and uses of the same NORTH CAROLINA STATE OF UNIVERSITY 2007-04-12 US disclosed
US-20070082349-A1 Photocrosslinking probes and uses of the same NORTH CAROLINA STATE OF UNIVERSITY 2007-04-12 US disclosed
US-20070054279-A1 Oligonucleotides comprising a ligand tethered to a modified or non-natural nucleobase ALNYLAM PHARMACEUTICALS (US) 2007-03-08 US disclosed
WO-2007014348-A2 PHOTOCROSSLINKING PROBES AND USES OF THE SAME NORTH CAROLINA UNIVERSITY (US) 2007-02-01 WO disclosed
EP-0703498-B1 Photosensitive resin composition and method for forming a photoresist pattern MITSUBISHI CHEM CORP (JP) 1997-12-29 EP disclosed
US-5698362-A CONTAINING A TRIARYLMETHANE DERIVATIVE; HIGH RESOLUTION, EXCELLENT IN DEPTH OF FOCUS AND PATTERN PROFILE, STORAGE STABLE MITSUBISHI CHEMICAL CORPORATION (JP) 1997-12-16 US disclosed
EP-0703498-A1 Photosensitive resin composition and method for forming a photoresist pattern MITSUBISHI CHEMICAL CORPORATION (JP) 1996-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030911-B2 Synthesis and biological activity of phosphoramidimidate and phosphoramidate DNA RNASEH1, RNASE1, DNASE1 CA4 2919/4885ESR1 4531/4885ESR2 3934/4885
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND RNGTT, PPA1, PNP CA4 3126/4885ESR1 2815/4885ESR2 4019/4885
US-20070082349-A1 Photocrosslinking probes and uses of the same DCLRE1A, LIG4, LIG1 CA4 3774/4885ESR1 2250/4885ESR2 3148/4885
US-20070123713-A1 Polycyclic dihydroxy compound and methods for preparation PAH, DDT, CYP24A1 CA4 478/4885ESR1 554/4885ESR2 1183/4885
US-20240209017-A1 STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING STING1, CGAS, MAVS CA4 4429/4885ESR1 3041/4885ESR2 3204/4885
US-20070054279-A1 Oligonucleotides comprising a ligand tethered to a modified or non-natural nucleobase DERA, NT5C3B, DUT CA4 3164/4885ESR1 664/4885ESR2 929/4885
US-11801306-B2 Compositions and methods for targeted RNA delivery PCSK9, LDLR, PCSK7 CA4 4512/4885ESR1 2919/4885ESR2 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.