Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424943 | 0.71 | L3MBTL1 (0.81) | L3MBTL1MAPTTP53MEN1KMT2A | |
| SCHEMBL18537726 | 0.70 | IKBKB (0.68) | IKBKBL3MBTL1MAPTPOLBKDM4E | |
| SCHEMBL18537603 | 0.68 | L3MBTL1 (0.48) | IKBKBL3MBTL1MAPTTP53MEN1 | |
| SCHEMBL425769 | 0.66 | MEN1 (0.77) | L3MBTL1MAPTTP53MEN1KMT2A | |
| SCHEMBL3173443 | 0.65 | IKBKB (1.00) | IKBKBL3MBTL1MAPTPOLBKDM4E | |
| SCHEMBL19000082 | 0.65 | IKBKB (0.64) | IKBKBL3MBTL1MAPTPOLBKDM4E | |
| SCHEMBL18537728 | 0.65 | IKBKB (0.65) | IKBKBL3MBTL1MAPTTP53MEN1 | |
| SCHEMBL431480 | 0.63 | LMNA (0.69) | L3MBTL1MAPTTP53MEN1KMT2A | |
| SCHEMBL18537602 | 0.62 | LMNA (0.47) | MAPTMEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL10978305 | 0.58 | ALDH1A1 (0.52) | MAPTTP53KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2400845-B1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | SIGA TECH INC (US) | 2017-02-22 | — | — | EP | disclosed |