Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | CCR9 | P51686 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10003531 | 0.89 | ALDH1A1 (0.48) | HTR6RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL10003527 | 0.89 | ALDH1A1 (0.48) | HTR6RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL20291498 | 0.89 | ALDH1A1 (0.48) | HTR6RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL28171535 | 0.88 | NPSR1 (0.43) | HTR6RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL29500522 | 0.88 | NOD2 (0.42) | HTR6RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL20291509 | 0.88 | NOD2 (0.42) | HTR6RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL10002618 | 0.88 | NOD2 (0.42) | HTR6RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL18537911 | 0.88 | NPSR1 (0.43) | HTR6RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL10002620 | 0.88 | NOD2 (0.42) | HTR6RAB9AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL11927245 | 0.87 | RAB9A (0.37) | HTR6RAB9AL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194751-A1 | INDOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF IN PHARMACEUTICAL DRUG | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2018-07-12 | — | — | US | disclosed |
| WO-2017028816-A1 | INDOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF IN PHARMACEUTICAL DRUG | 浙江海正药业股份有限公司 | 2017-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194751-A1 | INDOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF IN PHARMACEUTICAL DRUG | FGFR1, FGFR2, FGFR4 | HTR6 30/4885RAB9A 2293/4885L3MBTL1 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.