Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272755 | 0.92 | NFE2L2 (0.56) | NFE2L2CYP3A4KDM4ELMNATP53 | |
| SCHEMBL840235 | 0.92 | NFE2L2 (0.56) | NFE2L2CYP3A4KDM4ELMNATP53 | |
| SCHEMBL272756 | 0.92 | NFE2L2 (0.56) | NFE2L2CYP3A4KDM4ELMNATP53 | |
| SCHEMBL29982274 | 0.89 | CYP3A4 (0.56) | NFE2L2CYP3A4KDM4ELMNATP53 | |
| SCHEMBL13311231 | 0.88 | NFE2L2 (0.41) | NFE2L2CYP3A4KDM4ELMNATP53 | |
| SCHEMBL23665426 | 0.85 | MAPT (0.46) | NFE2L2CYP3A4KDM4ELMNATP53 | |
| SCHEMBL20179411 | 0.82 | NFE2L2 (0.48) | NFE2L2CYP3A4KDM4ELMNATP53 | |
| SCHEMBL7527708 | 0.81 | CYP3A4 (0.65) | NFE2L2CYP3A4KDM4ELMNATP53 | |
| SCHEMBL333123 | 0.81 | CYP3A4 (0.65) | NFE2L2CYP3A4KDM4ELMNATP53 | |
| SCHEMBL9461723 | 0.81 | CYP3A4 (0.65) | NFE2L2CYP3A4KDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10435626-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2019-10-08 | — | — | US | disclosed |
| US-20170267928-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-09-21 | — | — | US | disclosed |
| US-9701903-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20170073580-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-03-16 | — | — | US | disclosed |
| US-20170051204-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-23 | — | — | US | disclosed |