SCHEMBL272755

SCHEMBL272755

C/C=C/c1ccc(C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.56
CYP3A4 P08684 2/20 0.54
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
RELA Q04206 1/20 0.52
CA1 P00915 1/20 0.52
CYP2A6 P11509 1/20 0.50
FBP1 P09467 1/20 0.48
ALOX5 P09917 1/20 0.48
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ACHE P22303 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272756 1.00 NFE2L2 (0.56) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL840235 1.00 NFE2L2 (0.56) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL18538145 0.92 NFE2L2 (0.50) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL7527708 0.87 CYP3A4 (0.65) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL9461723 0.87 CYP3A4 (0.65) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL333123 0.87 CYP3A4 (0.65) NFE2L2CYP3A4LMNATP53TSHR
P-Xylene SCHEMBL9296384 0.87 CYP1B1 (0.52) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL17885977 0.86 NFE2L2 (0.45) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL15219791 0.86 NFE2L2 (0.45) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL10216097 0.86 NFE2L2 (0.45) NFE2L2CYP3A4LMNATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 710 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3902854-B1 POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER WITH BUTADIENE AND STYRENE BLOCKS AND A COMPATIBLE PLASTICISER MICHELIN & CIE (FR) 2025-10-15 EP claimed
US-12428552-B2 Polymeric composition comprising a thermoplastic elastomer with butadiene and styrene blocks and a compatible plasticizer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-09-30 US claimed
CN-113227175-B Polymer composition comprising thermoplastic elastomer with butadiene and styrene blocks and compatible plasticizer 米其林集团总公司 2024-03-29 CN claimed
WO-2023249093-A1 METHOD FOR PRODUCING COPOLYMER HAVING IMPROVED OIL RETAINABILITY 株式会社クラレ 2023-12-28 WO claimed
CN-114392291-A Folium artemisiae argyi burning backflow incense composition and preparation method and application thereof 黄山学院 2022-04-26 CN claimed
US-20220098402-A1 POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER WITH BUTADIENE AND STYRENE BLOCKS AND A COMPATIBLE PLASTICIZER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-03-31 US claimed
US-20220017676-A1 TIRE COMPRISING A POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER COMPRISING UNITS DERIVED FROM DIPHENYLENE ETHER MONOMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-01-20 US claimed
EP-3902854-A1 POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER WITH BUTADIENE AND STYRENE BLOCKS AND A COMPATIBLE PLASTICISER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-11-03 EP claimed
EP-3894235-A1 TYRE COMPRISING A POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER COMPRISING UNITS DERIVED FROM DIPHENYLENE ETHER MONOMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-10-20 EP claimed
CN-113227175-A Polymer composition comprising a thermoplastic elastomer with butadiene and styrene blocks and a compatible plasticizer 米其林集团总公司 2021-08-06 CN claimed
EP-3541635-B1 TIRE COMPRISING A BLOCK COPOLYMER COMPRISING AN ELASTOMERIC BLOCK HAVING UNITS OF ISOBUTYLENE AND HALOGENOALKYLSTYRENE MICHELIN & CIE (FR) 2020-12-30 EP claimed
US-20200331868-A1 COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF USA Elixiria Biotech Inc. 2020-10-22 US claimed
WO-2020136194-A1 POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER WITH BUTADIENE AND STYRENE BLOCKS AND A COMPATIBLE PLASTICISER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-07-02 WO claimed
WO-2020120390-A1 TYRE COMPRISING A POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER COMPRISING UNITS DERIVED FROM DIPHENYLENE ETHER MONOMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-06-18 WO claimed
EP-3642281-A1 POLYMER COMPOSITION COMPRISING A BRANCHED THERMOPLASTIC ELASTOMER AND A THERMOPLASTIC STYRENE POLYMER Compagnie Générale des Etablissements Michelin (FR) 2020-04-29 EP claimed
CN-110799591-A Polymer composition comprising a branched thermoplastic elastomer and a thermoplastic styrene polymer 米其林集团总公司 2020-02-14 CN claimed
EP-3541635-A1 PNEUMATIC TYRE COMPRISING A BLOCK COPOLYMER COMPRISING AN ELASTOMER BLOCK WITH ISOBUTYLENE AND HALOGENOALKYL STYRENE UNITS Compagnie Générale des Etablissements Michelin (FR) 2019-09-25 EP claimed
WO-2018234278-A1 POLYMER COMPOSITION COMPRISING A BRANCHED THERMOPLASTIC ELASTOMER AND A THERMOPLASTIC STYRENE POLYMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-12-27 WO claimed
US-7241837-B2 Vibration damper composition KANEKA CORPORATION (JP) 2007-07-10 US claimed
US-4956123-A REACTING A STYRENE TYPE COMPOUND WITH A DIHALOACYL PEROXIDE TO MAKE A FLUOROALKYLAROMATIC ESTER NIPPON OILS & FATS COMPANY, LTD. (JP) 1990-09-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200331868-A1 COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF PPARA, PPARG, PPARD NFE2L2 733/4885CYP3A4 869/4885LMNA 3582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.