SCHEMBL840235

SCHEMBL840235

C/C=C\c1ccc(C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.56
CYP3A4 P08684 2/20 0.54
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
RELA Q04206 1/20 0.52
CA1 P00915 1/20 0.52
CYP2A6 P11509 1/20 0.50
FBP1 P09467 1/20 0.48
ALOX5 P09917 1/20 0.48
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ACHE P22303 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272756 1.00 NFE2L2 (0.56) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL272755 1.00 NFE2L2 (0.56) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL18538145 0.92 NFE2L2 (0.50) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL7527708 0.87 CYP3A4 (0.65) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL9461723 0.87 CYP3A4 (0.65) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL333123 0.87 CYP3A4 (0.65) NFE2L2CYP3A4LMNATP53TSHR
P-Xylene SCHEMBL9296384 0.87 CYP1B1 (0.52) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL17885977 0.86 NFE2L2 (0.45) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL15219791 0.86 NFE2L2 (0.45) NFE2L2CYP3A4LMNATP53TSHR
SCHEMBL10216097 0.86 NFE2L2 (0.45) NFE2L2CYP3A4LMNATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114392291-A Folium artemisiae argyi burning backflow incense composition and preparation method and application thereof 黄山学院 2022-04-26 CN claimed
WO-2021050786-A1 CANNABIN OID COMPOSITIONS WITH IMPROVED ORGANOLEPTIC AND THERAPEUTIC PROPERTIES, METHOD OF PRODUCTION, AND USE THEREOF CALIFORNIA AMBER INC. (US) 2021-03-18 WO claimed
US-20210068444-A1 CANNABINOID COMPOSITIONS WITH IMPROVED ORGANOLEPTIC AND THERAPEUTIC PROPERTIES, METHOD OF PRODUCTION, AND USE THEREOF CALIFORNIA AMBER INC. 2021-03-11 US claimed
EP-2310446-B1 ACTIVATED HALO-CONTAINING ARALKYLSILANE MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-23 EP claimed
WO-2013173332-A1 METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN Vertichem Corporation (CA) 2013-11-21 WO claimed
CN-102177197-B Activated halo-containing aralkylsilane MOMENTIVE PERFORMANCE MAT INC 2013-11-06 CN claimed
US-20130232852-A1 METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN THESIS CHEMISTRY, LLC (US) 2013-09-12 US claimed
US-20130232853-A1 METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN THESIS CHEMISTRY, LLC (US) 2013-09-12 US claimed
WO-2013134756-A1 A METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN Vertichem Corporation (CA) 2013-09-12 WO claimed
US-8143336-B2 Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-27 US claimed
CN-102177197-A Activated halo-containing aralkylsilane MOMENTIVE PERFORMANCE MAT INC 2011-09-07 CN claimed
EP-2310446-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE Momentive Performance Materials Inc. (US) 2011-04-20 EP claimed
WO-2010017370-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-02-11 WO claimed
US-20100036018-A1 ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2010-02-11 US claimed
EP-4397715-A1 RESIN COMPOSITION AND MOLDED ARTICLE Mitsubishi Engineering-Plastics Corporation (JP) 2024-07-10 EP disclosed
US-12031032-B2 Thermoplastic resin including a flame retardant and organopolysiloxane MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2024-07-09 US disclosed
EP-3546521-B1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENG PLASTICS CORP (JP) 2024-04-03 EP disclosed
US-7419998-B2 Therapeutic methods and compositions involving isoflavones NOVOGEN RESEARCH PTY LTD (AU) 2008-09-02 US disclosed
US-7202273-B2 Therapeutic methods and compositions involving isoflavones NOVOGEN RESEARCH PTY LTD (AU) 2007-04-10 US disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130232852-A1 METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN DCXR, AGL, GLO1 NFE2L2 2707/4885CYP3A4 343/4885LMNA 698/4885
US-20130232853-A1 METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN HAAO, HAO2, HACL2 NFE2L2 1174/4885CYP3A4 123/4885LMNA 1448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.