SCHEMBL18539632

SCHEMBL18539632

CCOCn1cc(/C=N/OC(C)=O)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
KMT2A Q03164 6/20 0.44
MAPT P10636 9/20 0.44
LMNA P02545 6/20 0.44
MEN1 O00255 5/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
HPGD P15428 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18539727 0.89 ALDH1A1 (0.48) ALDH1A1KMT2AMAPTLMNAMEN1
SCHEMBL213761 0.78 MAPT (0.54) ALDH1A1KMT2AMAPTLMNAMEN1
SCHEMBL213762 0.78 MAPT (0.54) ALDH1A1KMT2AMAPTLMNAMEN1
SCHEMBL5820805 0.70 ALDH1A1 (0.64) ALDH1A1KMT2AMAPTLMNAMEN1
SCHEMBL18539720 0.70 MAPT (0.51) ALDH1A1KMT2AMAPTLMNAMEN1
SCHEMBL18539669 0.70 CNR2 (0.48) ALDH1A1KMT2AMAPTLMNAMEN1
SCHEMBL13078705 0.67 ALDH1A1 (0.40) ALDH1A1KMT2AMAPTLMNAMEN1
SCHEMBL13044364 0.67 GRIN2D (0.51) ALDH1A1KMT2AMAPTLMNAMEN1
SCHEMBL13078614 0.66 GCGR (0.44) ALDH1A1KMT2ALMNAMEN1SMN1; SMN2
SCHEMBL13490857 0.65 POLB (0.66) ALDH1A1KMT2AMAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438134-B1 POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT ADEKA CORP (JP) 2021-05-05 EP disclosed
EP-3438134-A1 POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT Adeka Corporation (JP) 2019-02-06 EP disclosed
US-10189847-B2 Oxime ester compound and photopolymerization initiator containing said compound ADEKA CORPORATION (JP) 2019-01-29 US disclosed
US-20170166575-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAID COMPOUND ADEKA CORPORATION (JP) 2017-06-15 US disclosed
US-20170166575-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAID COMPOUND ADEKA CORPORATION (JP) 2017-06-15 US disclosed
WO-2017030005-A1 COMPOSITION 株式会社ADEKA 2017-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166575-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAID COMPOUND RB1, PRMT9, KDM2B ALDH1A1 1211/4885KMT2A 224/4885MAPT 3454/4885
US-10189847-B2 Oxime ester compound and photopolymerization initiator containing said compound PPOX, CCNO, MRTO4 ALDH1A1 1193/4885KMT2A 185/4885MAPT 2515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.