Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855106 | 0.95 | MLYCD (0.49) | CA2MLYCDNAAATMEM97SIGMAR1 | |
| SCHEMBL1855672 | 0.89 | CA2 (0.57) | CA2MLYCDEPHX2NAAATMEM97 | |
| SCHEMBL1850884 | 0.85 | NAAA (0.44) | CA2MLYCDNAAATMEM97SIGMAR1 | |
| SCHEMBL5047490 | 0.83 | MLYCD (0.53) | CA2MLYCDNAAATMEM97SIGMAR1 | |
| SCHEMBL1853427 | 0.82 | TMEM97 (0.56) | CA2MLYCDEPHX2NAAATMEM97 | |
| SCHEMBL1852987 | 0.82 | TMEM97 (0.56) | CA2MLYCDEPHX2NAAATMEM97 | |
| SCHEMBL1854307 | 0.80 | NAAA (0.48) | CA2NAAATMEM97SIGMAR1NAMPT | |
| SCHEMBL1853434 | 0.80 | TMEM97 (0.53) | CA2MLYCDNAAATMEM97SIGMAR1 | |
| SCHEMBL27601057 | 0.79 | MLYCD (0.55) | CA2MLYCDNAAAL3MBTL1NAMPT | |
| SCHEMBL1857574 | 0.78 | NAAA (0.57) | CA2MLYCDNAAATMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-B1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | MERCK SERONO SA (CH) | 2011-05-25 | — | — | EP | claimed |