Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044129 | 0.89 | MRGPRX4 (0.47) | MLYCDCA2L3MBTL1NAAAALDH1A1 | |
| SCHEMBL1855106 | 0.88 | MLYCD (0.49) | MLYCDCA2L3MBTL1NAAATHRA | |
| SCHEMBL27601057 | 0.85 | MLYCD (0.55) | MLYCDCA2L3MBTL1NAAATHRA | |
| SCHEMBL1853992 | 0.83 | CA2 (0.46) | MLYCDCA2L3MBTL1NAAATHRA | |
| SCHEMBL13577948 | 0.83 | MLYCD (0.59) | MLYCDCA2L3MBTL1NAAATHRA | |
| SCHEMBL5045657 | 0.80 | NAAA (0.71) | MLYCDCA2L3MBTL1NAAATHRA | |
| SCHEMBL5045529 | 0.80 | TRPV1 (0.60) | L3MBTL1NAAASMN1; SMN2TMEM97SIGMAR1 | |
| SCHEMBL5044615 | 0.80 | TMEM97 (0.60) | MLYCDCA2L3MBTL1NAAATHRA | |
| SCHEMBL1850884 | 0.78 | NAAA (0.44) | MLYCDCA2L3MBTL1NAAAALDH1A1 | |
| SCHEMBL5044180 | 0.77 | MRGPRX4 (0.48) | MLYCDCA2NAAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |