SCHEMBL2479271

SCHEMBL2479271

C=CCCc1ccc(-c2ccc(-c3ccc(CC)cc3)cc2)cc1F

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.36
RARA P10276 2/20 0.36
RARG P13631 1/20 0.36
TAAR1 Q96RJ0 2/20 0.34
CYP17A1 P05093 3/20 0.33
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
KIF11 P52732 1/20 0.33
FAAH O00519 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
MAPT P10636 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP19A1 P11511 1/20 0.31
MAOB P27338 1/20 0.31
LMNA P02545 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2478899 0.85 RARB (0.39) RARBRARARARGTAAR1CYP17A1
SCHEMBL18540031 0.84 HTR2A (0.38) RARBRARARARGTAAR1CYP17A1
SCHEMBL18540216 0.84 HTR2A (0.36) RARBRARARARGTAAR1CYP17A1
SCHEMBL18540229 0.84 TAAR1 (0.36) RARBRARARARGTAAR1CYP17A1
SCHEMBL18540147 0.83 RARB (0.44) RARBRARARARGMAPTCNR2
SCHEMBL12760546 0.82 RARB (0.40) RARBRARARARGTAAR1CYP17A1
SCHEMBL9999856 0.82 RARB (0.40) RARBRARARARGTAAR1CYP17A1
SCHEMBL16377214 0.82 RARB (0.43) RARBRARARARGTAAR1CYP17A1
SCHEMBL20803619 0.80 NAAA (0.45) CYP17A1FAAHMAPT
SCHEMBL18540224 0.80 MAOB (0.41) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1970362-B1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2011-10-12 EP disclosed
EP-1970362-B1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2011-10-12 EP disclosed
US-7749403-B2 Monofluorinated terphenyl compound having alkenyl, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2010-07-06 US disclosed
US-7749403-B2 Monofluorinated terphenyl compound having alkenyl, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2010-07-06 US disclosed
US-20090206300-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2009-08-20 US disclosed
US-20090206300-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2009-08-20 US disclosed
EP-1970362-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2008-09-17 EP disclosed
EP-1970362-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090206300-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE LEF1, FZD7, HTR1D RARB 3441/4885RARA 2495/4885RARG 3629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.