SCHEMBL18540402

SCHEMBL18540402

Cc1cc(C)c(N(c2cccc(-c3cc(CC(C)C)c([Si](C)(C)C)cn3)c2)c2cccc(-c3cc(CC(C)C)c([Si](C)(C)C)cn3)c2)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18540377 0.84 PIM1 (0.35) PIM1PIM3PIM2
SCHEMBL17637117 0.78 KMO (0.37)
SCHEMBL17637115 0.77 ADORA1 (0.38)
SCHEMBL18540389 0.77 TP53 (0.43)
SCHEMBL23416511 0.76 NPC1 (0.35) PIM1
SCHEMBL18540388 0.76 WNK1 (0.36)
SCHEMBL18540374 0.74 KDM1A (0.35) PIM1PIM3PIM2
SCHEMBL17811395 0.72 SGK1 (0.36)
SCHEMBL18540387 0.72 CYP2A6 (0.35) PIM1PIM3PIM2
SCHEMBL18540379 0.70 KDM1A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11211571-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-28 US disclosed
US-20170054095-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2017-02-23 US disclosed
US-20170054095-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2017-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11211571-B2 Organometallic compound and organic light-emitting device including the same CRY1, LEF1, POU2F1 PIM1 536/4885PIM3 971/4885PIM2 996/4885
US-20170054095-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, LEF1, POU2F1 PIM1 536/4885PIM3 971/4885PIM2 996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.