SCHEMBL18540765

SCHEMBL18540765

Cc1cccc(C(=O)c2ccccc2O)c1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.71
KMT2A Q03164 2/20 0.71
CYP2C9 P11712 1/20 0.71
ALDH1A1 P00352 8/20 0.60
HPGD P15428 5/20 0.60
KDM4E B2RXH2 5/20 0.60
HSD17B10 Q99714 4/20 0.60
TRPA1 O75762 1/20 0.54
SPR P35270 1/20 0.51
LMNA P02545 4/20 0.50
HTT P42858 3/20 0.50
TSHR P16473 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MAPK1 P28482 1/20 0.50
TP53 P04637 1/20 0.50
GSTA1 P08263 2/20 0.49
CYP1A2 P05177 1/20 0.49
PGR P06401 1/20 0.49
ADORA3 P0DMS8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26440502 0.90 CYP3A4 (0.68) CYP3A4KMT2ACYP2C9ALDH1A1HPGD
SCHEMBL1758307 0.90 KMT2A (0.78) CYP3A4KMT2ACYP2C9ALDH1A1HPGD
SCHEMBL3358950 0.86 SPR (0.56) CYP3A4KMT2ACYP2C9ALDH1A1HPGD
SCHEMBL301928 0.84 LIG1 (0.55) CYP3A4KMT2ACYP2C9ALDH1A1HPGD
SCHEMBL30740067 0.84 LIG1 (0.55) CYP3A4KMT2ACYP2C9ALDH1A1HPGD
Hydroxytoluic Acid SCHEMBL8428999 0.83 ALDH1A1 (0.81) CYP3A4KMT2ACYP2C9ALDH1A1HPGD
SCHEMBL21812540 0.83 CYP3A4 (1.00) CYP3A4KMT2ACYP2C9ALDH1A1HPGD
2,2'-Dihydroxybenzphenone SCHEMBL18422 0.81 HPGD (0.67) CYP3A4KMT2AALDH1A1HPGDKDM4E
2,2'-Dihydroxybenzphenone SCHEMBL29572496 0.81 HPGD (0.67) CYP3A4KMT2AALDH1A1HPGDKDM4E
SCHEMBL26441772 0.81 KMT2A (0.56) CYP3A4KMT2ACYP2C9ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9851314-B2 Chiral metal complex and use thereof for analyzing chirality of charged compound by 1H NMR spectroscopy KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-12-26 US disclosed
US-20170052131-A1 NOVEL CHIRAL METAL COMPLEX AND USE THEREOF FOR ANALYZING CHIRALITY OF CHARGED COMPOUND BY 1H NMR SPECTROSCOPY KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170052131-A1 NOVEL CHIRAL METAL COMPLEX AND USE THEREOF FOR ANALYZING CHIRALITY OF CHARGED COMPOUND BY 1H NMR SPECTROSCOPY CROCC, COIL, NCAPD2 CYP3A4 3410/4885KMT2A 2292/4885CYP2C9 3667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.