SCHEMBL3358950

SCHEMBL3358950

Cc1ccccc1C(=O)c1ccccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPR P35270 1/20 0.56
HPGD P15428 5/20 0.55
ALDH1A1 P00352 5/20 0.55
KDM4E B2RXH2 5/20 0.55
LMNA P02545 4/20 0.55
HSD17B10 Q99714 3/20 0.55
HTT P42858 3/20 0.55
MAPK1 P28482 1/20 0.55
LIG1 P18858 1/20 0.53
GSTA1 P08263 2/20 0.53
CYP3A4 P08684 2/20 0.53
HIF1A Q16665 2/20 0.53
CYP1A2 P05177 1/20 0.53
PGR P06401 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
AR P10275 1/20 0.53
CHRM1 P11229 1/20 0.53
ALOX15 P16050 1/20 0.53
TBXA2R P21731 1/20 0.53
SLC6A2 P23975 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333141 0.89 CYP3A4 (0.55) HPGDALDH1A1HTTCYP3A4SMN1; SMN2
SCHEMBL29387256 0.89 CYP3A4 (0.55) HPGDALDH1A1HTTCYP3A4SMN1; SMN2
SCHEMBL10669335 0.86 CYP3A4 (0.59) HPGDALDH1A1HTTCYP3A4SMN1; SMN2
2,2'-Dihydroxybenzphenone SCHEMBL29572496 0.86 HPGD (0.67) SPRHPGDALDH1A1KDM4ELMNA
2,2'-Dihydroxybenzphenone SCHEMBL18422 0.86 HPGD (0.67) SPRHPGDALDH1A1KDM4ELMNA
SCHEMBL18540765 0.86 CYP3A4 (0.71) SPRHPGDALDH1A1KDM4ELMNA
SCHEMBL9172081 0.86 TRPA1 (0.54) SPRHPGDALDH1A1KDM4ELMNA
SCHEMBL455832 0.84 LIG1 (0.64) SPRHPGDALDH1A1KDM4ELMNA
2,2'-Dihydroxybenzphenone SCHEMBL11145317 0.84 LIG1 (0.64) SPRHPGDALDH1A1KDM4ELMNA
2,2'-Dihydroxybenzphenone SCHEMBL6652370 0.84 LIG1 (0.64) SPRHPGDALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9855207-B2 UV-photo-protecting cosmetic composition MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2018-01-02 US disclosed
US-20170360660-A1 MICROCAPSULES BASF GRENZACH GMBH (DE) 2017-12-21 US disclosed
US-20170231889-A1 Sunscreen Compositions Comprising Colour Pigments BASF SE (DE) 2017-08-17 US disclosed
US-9656103-B2 Light protecting-effective cosmetic or dermatological preparations BASF SE (DE) 2017-05-23 US disclosed
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS BASF SE (DE) 2016-03-10 US disclosed
US-20140308225-A1 Use of Oleogels in UV Absorber Compositions BASF SE (DE) 2014-10-16 US disclosed
US-8404705-B2 Naphthalene amidine imides BASF SE (DE) 2013-03-26 US disclosed
US-20120121524-A1 PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS MUELLER STEFAN (DE) 2012-05-17 US disclosed
US-8119107-B2 Photo-stable cosmetic or dermatological compositions BASF SE (DE) 2012-02-21 US disclosed
US-20110033400-A1 SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS BASF SE (US) 2011-02-10 US disclosed
US-20100143272-A1 Photo-stable cosmetic or dermatological compositions CIBA SPECIALTY CHEMICALS CORPORATION 2010-06-10 US disclosed
EP-2192597-A1 POLYMER ELECTROLYTE COMPOSITION Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
EP-1801176-B1 Coating compositions and method for the surface protection of plastic substrate SHINETSU CHEMICAL CO (JP) 2009-03-18 EP disclosed
US-20090035238-A1 UV FILTER CAPSULE CONTAINING AN AMINO-SUBSTITUTED HYDROXYBENZOPHENONE MERCK PATENT GMBH (DE) 2009-02-05 US disclosed
US-20080075746-A1 Dispersing insoluble or sparingly soluble micronized substance in oil or water phase; adding soluble ultraviolet radiation filter that is not a cosmetic UV absorber; remarkable increase in (SPF) sun protection factor; sunscreen agents CIBA SPECIALTY CHEMICALS CORPORATION 2008-03-27 US disclosed
US-7311897-B2 Triazines which are symmetrically substituted by phenyl, biphenyl, triphenyl or naphthyl can be used as highly effective UV absorbers for cosmetic applications CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-12-25 US disclosed
US-20070219275-A1 Use of Benzophenone Uv Filters for Preventing Tanning BASCHONG WERNER 2007-09-20 US disclosed
EP-1801176-A1 Coating compositions and method for the surface protection of plastic substrate Shin-Etsu Chemical Co., Ltd. (JP) 2007-06-27 EP disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360660-A1 MICROCAPSULES ADH5, IPMK, CHKB SPR 4299/4885HPGD 904/4885ALDH1A1 2009/4885
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS ERCC5, ERCC1, TTPA SPR 3227/4885HPGD 859/4885ALDH1A1 809/4885
US-20120121524-A1 PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS NISCH, CUTA, MITF SPR 1745/4885HPGD 422/4885ALDH1A1 241/4885
US-20110033400-A1 SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS TYR, ERCC1, ERCC4 SPR 2491/4885HPGD 469/4885ALDH1A1 221/4885
US-20090035238-A1 UV FILTER CAPSULE CONTAINING AN AMINO-SUBSTITUTED HYDROXYBENZOPHENONE TYR, MITF, UROD SPR 3240/4885HPGD 318/4885ALDH1A1 652/4885
US-20070219275-A1 Use of Benzophenone Uv Filters for Preventing Tanning C1R, CBR3, AOC3 SPR 3697/4885HPGD 3218/4885ALDH1A1 2787/4885
US-20080075746-A1 Dispersing insoluble or sparingly soluble micronized substance in oil or water phase; adding soluble ultraviolet radiation filter that is not a cosmetic UV absorber; remarkable increase in (SPF) sun protection factor; sunscreen agents CUTA, MITF, MIF SPR 1739/4885HPGD 710/4885ALDH1A1 1973/4885
US-20170231889-A1 Sunscreen Compositions Comprising Colour Pigments TYR, ERCC1, ERCC4 SPR 2491/4885HPGD 469/4885ALDH1A1 221/4885
US-20100143272-A1 Photo-stable cosmetic or dermatological compositions DBF4, CUTA, ARSA SPR 3895/4885HPGD 1981/4885ALDH1A1 325/4885
US-20140308225-A1 Use of Oleogels in UV Absorber Compositions ERCC4, ERCC1, OGG1 SPR 2368/4885HPGD 224/4885ALDH1A1 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.