SCHEMBL18541302

SCHEMBL18541302

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc(-c5ccc6c(c5)c5ccccc5c5ccc(-c7ccc8sc9c(ccc%10c%11ccccc%11n(-c%11nc(-c%12ccccc%12)nc(-c%12ccccc%12)n%11)c%109)c8c7)cc56)c4)c3)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 1/20 0.34
PIM1 P11309 2/20 0.31
PIM2 Q9P1W9 2/20 0.31
PIM3 Q86V86 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24952451 0.97 LIMK1 (0.35) LIMK1PIM1PIM2PIM3
SCHEMBL18879799 0.94 LIMK1 (0.34) LIMK1
SCHEMBL27324992 0.94 LIMK1 (0.39) LIMK1PIM1PIM2PIM3
SCHEMBL15126644 0.94 LIMK1 (0.39) LIMK1PIM1PIM2PIM3
SCHEMBL20154391 0.92 ALOX5 (0.33) LIMK1
SCHEMBL15625602 0.92 CYP1A2 (0.34) LIMK1PIM1PIM2PIM3
SCHEMBL24217096 0.92 ALOX5 (0.34) LIMK1PIM1PIM2PIM3
SCHEMBL24901020 0.91 LIMK1 (0.34) LIMK1PIM1PIM2PIM3
SCHEMBL18505473 0.90 TNKS (0.33) LIMK1
SCHEMBL23598465 0.90 TNKS (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345825-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230303605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2023-09-28 US disclosed
US-20230126221-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-11522140-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-12-06 US disclosed
US-20220127291-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-28 US disclosed
US-11180519-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-23 US disclosed
US-20210351362-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-11-11 US disclosed
US-11152579-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-19 US disclosed
US-20200144519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 US disclosed
US-20190248818-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed
US-20190214582-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-07-11 US disclosed
US-20180205022-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-07-19 US disclosed
US-20180182981-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-06-28 US disclosed
US-20180179237-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-06-28 US disclosed
US-20170054087-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP LIMK1 154/4885PIM1 2589/4885PIM2 2573/4885
US-20180179237-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP LIMK1 154/4885PIM1 2589/4885PIM2 2573/4885
US-20190248818-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR LIMK1 382/4885PIM1 2351/4885PIM2 2731/4885
US-20200144519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 LIMK1 1263/4885PIM1 3598/4885PIM2 3544/4885
US-11180519-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR LIMK1 382/4885PIM1 2351/4885PIM2 2731/4885
US-20180205022-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, OPA1 LIMK1 1000/4885PIM1 3178/4885PIM2 2917/4885
US-20190214582-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP LIMK1 866/4885PIM1 3375/4885PIM2 2896/4885
US-20180182981-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CACNA2D2, RABGGTA, NUDT1 LIMK1 254/4885PIM1 975/4885PIM2 624/4885
US-11152579-B2 Organic electroluminescent materials and devices CACNA2D2, RABGGTA, NUDT1 LIMK1 254/4885PIM1 975/4885PIM2 624/4885
US-20220127291-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OCIAD2, OXSR1 LIMK1 446/4885PIM1 3947/4885PIM2 3447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.