SCHEMBL18879799

SCHEMBL18879799

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc(-c5ccc6c(c5)c5ccccc5c5ccc(-c7ccc8c(c7)sc7c8ccc8c9ccccc9n(-c9nc(-c%10ccccc%10)nc(-c%10ccccc%10)n9)c87)cc56)c4)c3)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 6/20 0.34
LIMK2 P53671 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18541302 0.94 LIMK1 (0.34) LIMK1
SCHEMBL20154391 0.92 ALOX5 (0.33) LIMK1
SCHEMBL24217096 0.92 ALOX5 (0.34) LIMK1
SCHEMBL24952451 0.91 LIMK1 (0.35) LIMK1
SCHEMBL18505473 0.90 TNKS (0.33) LIMK1
SCHEMBL23598465 0.90 TNKS (0.34)
SCHEMBL18505509 0.88 LIMK1 (0.34) LIMK1
SCHEMBL19129732 0.88 LIMK1 (0.34) LIMK1
SCHEMBL26388643 0.88 MEN1 (0.37) LIMK1LIMK2
SCHEMBL21965518 0.87 TNKS (0.32) LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-20230276694-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-31 US disclosed
US-11349087-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-05-31 US disclosed
US-10998507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-05-04 US disclosed
US-20200350502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed
US-20170148988-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170148988-A1 Organic Electroluminescent Materials and Devices CPNE4, MT-ND5, CENPE LIMK1 342/4885LIMK2 663/4885
US-20200350502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OSBPL3, OSBP2 LIMK1 518/4885LIMK2 964/4885
US-11349087-B2 Organic electroluminescent materials and devices ICMT, OR51E2, ICOSLG LIMK1 684/4885LIMK2 601/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 LIMK1 1866/4885LIMK2 2515/4885
US-20230276694-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OSBP, OCIAD2 LIMK1 1866/4885LIMK2 2515/4885
US-10998507-B2 Organic electroluminescent materials and devices CPNE4, MT-ND5, CENPE LIMK1 342/4885LIMK2 663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.