SCHEMBL1854500

SCHEMBL1854500

CCCCCC(CC)c1nccn1C

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 2/20 0.38
NR1I2 O75469 1/20 0.35
CYP2D6 P10635 1/20 0.34
MAPT P10636 2/20 0.33
LPO P22079 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20994722 0.98 TLR8 (0.39) TLR8L3MBTL1ALDH1A1POLBKMT2A
SCHEMBL19582677 0.95 L3MBTL1 (0.40) TLR8L3MBTL1ALDH1A1POLBKMT2A
SCHEMBL19087084 0.92 TLR8 (0.41) TLR8L3MBTL1ALDH1A1POLBKMT2A
SCHEMBL21024640 0.92 TLR8 (0.41) TLR8L3MBTL1ALDH1A1POLBKMT2A
SCHEMBL27895992 0.92 TLR8 (0.41) TLR8L3MBTL1ALDH1A1POLBKMT2A
SCHEMBL20372906 0.92 TLR8 (0.41) TLR8L3MBTL1ALDH1A1POLBKMT2A
SCHEMBL20098274 0.90 TLR8 (0.40) TLR8L3MBTL1ALDH1A1POLBKMT2A
SCHEMBL28717092 0.90 TLR8 (0.40) TLR8L3MBTL1ALDH1A1POLBKMT2A
Hydrochloric Acid SCHEMBL28717680 0.89 TLR8 (0.41) TLR8L3MBTL1ALDH1A1POLBKMT2A
SCHEMBL14148932 0.84 L3MBTL1 (0.46) L3MBTL1ALDH1A1POLBKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650498-A1 FLUID CONTACTING DEVICE Aurotec GmbH (AT) 2025-11-19 EP claimed
US-7858802-B2 Method of preparing ionic liquids BASF SE (DE) 2010-12-28 US claimed
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures COVESTRO DEUTSCHLAND AG (DE) 2026-02-24 US disclosed
EP-4650498-A1 FLUID CONTACTING DEVICE Aurotec GmbH (AT) 2025-11-19 EP disclosed
EP-4157912-B1 COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES COVESTRO DEUTSCHLAND AG (DE) 2024-05-22 EP disclosed
EP-3997183-B1 METHOD FOR THE PRODUCTION OF ISOCYANURATES FROM URETDIONES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-10-04 EP disclosed
EP-3555070-B1 AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF EPIZYME INC (US) 2023-08-09 EP disclosed
US-20230192941-A1 COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES COVESTRO DEUTSCHLAND AG (DE) 2023-06-22 US disclosed
EP-4157912-A1 COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES Covestro Deutschland AG (DE) 2023-04-05 EP disclosed
US-20220348708-A1 METHOD FOR PRODUCING ISOCYANURATES FROM URETDIONES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-11-03 US disclosed
US-20220251280-A1 PROCESS OF PREPARING ALLOPHANATE- AND/OR THIOALLOPHANATE GROUP-CONTAINING COMPOUNDS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-08-11 US disclosed
CN-1914181-A Method for preparing ionic liquid BASF AG (DE) 2007-02-14 CN disclosed
EP-1711472-A1 MEHTOD FOR PRODUCING IONIC LIQUIDS BASF AKTIENGESELLSCHAFT (DE) 2006-10-18 EP disclosed
CN-1826326-A Method for the production of purified 1,3-substituted imidazolium salts BASF AG (DE) 2006-08-30 CN disclosed
CN-1826302-A Method for extracting impurities using ionic liquids BASF AG (DE) 2006-08-30 CN disclosed
US-20060149074-A1 Method for the production of purified 1,3-substituted imidazolium salts BASF AKTIENGESELLSCHAFT (DE) 2006-07-06 US disclosed
EP-1648845-A1 METHOD FOR EXTRACTING IMPURITIES USING IONIC LIQUIDS BASF AKTIENGESELLSCHAFT (DE) 2006-04-26 EP disclosed
WO-2005070896-A1 MEHTOD FOR PRODUCING IONIC LIQUIDS BASF AKTIENGESELLSCHAFT (DE) 2005-08-04 WO disclosed
WO-2005019137-A1 METHOD FOR EXTRACTING IMPURITIES USING IONIC LIQUIDS BASF AKTIENGESELLSCHAFT (DE) 2005-03-03 WO disclosed
EP-1398318-A1 Process for conducting chemical reactions in a liquid phase in the presence of a catalyst and a 1,3-substituted imidazolium salt BASF AKTIENGESELLSCHAFT (DE) 2004-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures URB2, UQCRB, UQCRC2 TLR8 4009/4885L3MBTL1 3338/4885ALDH1A1 1357/4885
US-20060149074-A1 Method for the production of purified 1,3-substituted imidazolium salts HIRA, HAO2, HACL2 TLR8 4532/4885L3MBTL1 4844/4885ALDH1A1 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.