Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TCF4 | P15884 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12009015 | 1.00 | MYC (0.59) | MYCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL13446960 | 0.90 | MYC (0.62) | MYCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL12009080 | 0.89 | MYC (0.63) | MYCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL18545527 | 0.83 | ALDH1A1 (0.59) | MYCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL12009070 | 0.83 | ALDH1A1 (0.59) | MYCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL12009085 | 0.81 | TCF4 (0.67) | MYCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL12009729 | 0.79 | S1PR4 (0.60) | MYCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL12009094 | 0.79 | MYC (0.77) | MYCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL18545498 | 0.79 | MYC (0.77) | MYCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL12009028 | 0.78 | S1PR4 (0.58) | MYCALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170049751-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | DASGUPTA RAMANUJ (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049751-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | CTNNB1, CTNNA1, CTNNBL1 | MYC 93/4885ALDH1A1 413/4885SMN1; SMN2 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.