SCHEMBL18545979

SCHEMBL18545979

CC(=O)c1ccc2cc(COc3ccc(C(=O)c4ccccc4)c(O)c3)ccc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.60
HTT P42858 4/20 0.60
ALDH1A1 P00352 3/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
HPGD P15428 2/20 0.55
LMNA P02545 1/20 0.55
CYP1A2 P05177 1/20 0.55
PGR P06401 1/20 0.55
CYP2D6 P10635 1/20 0.55
SLC6A2 P23975 1/20 0.55
PDE4A P27815 1/20 0.55
MAPK1 P28482 1/20 0.55
CYP2C19 P33261 1/20 0.55
HRH1 P35367 1/20 0.55
SLC6A3 Q01959 1/20 0.55
PDE4D Q08499 1/20 0.55
MAOA P21397 7/20 0.51
CTSD P07339 1/20 0.49
PTGES O14684 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5393386 0.83 SRD5A2 (0.65) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL7739310 0.82 NPC1 (0.63) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL26863 0.82 MAOB (0.71) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL29481015 0.82 MAOB (0.71) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2
Benzophenone SCHEMBL28215327 0.81 MAOB (0.69) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL2686883 0.81 PTGES (0.70) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL3298563 0.79 SRD5A2 (0.63) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2
Acetic Acid SCHEMBL9428134 0.79 SMN1; SMN2 (0.70) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL7737574 0.78 MAOB (0.62) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL23851943 0.78 MEN1 (0.68) MAOBHTTALDH1A1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting TOKYO ELECTRON LIMITED (JP) 2018-07-17 US disclosed
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method JSR CORPORATION (JP) 2018-07-10 US disclosed
US-9971247-B2 Pattern-forming method OSAKA UNIVERSITY (JP) 2018-05-15 US disclosed
US-20170131633-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-05-11 US disclosed
US-20170052450-A1 PATTERN-FORMING METHOD OSAKA UNIVERSITY (JP) 2017-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting ASIC1, ASIC3, CLTA MAOB 3685/4885HTT 4610/4885ALDH1A1 1963/4885
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method SLC11A2, XRCC5, RAD54L MAOB 4309/4885HTT 3483/4885ALDH1A1 2183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.