Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 12/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963814 | 0.91 | MAOB (0.69) | NPC1MAPTMRGPRX4MAOBALDH1A1 | |
| SCHEMBL9186121 | 0.89 | MAOB (0.74) | MRGPRX4MAOBMAOA | |
| SCHEMBL7737574 | 0.86 | MAOB (0.62) | NPC1MAPTMAOBALOX5ALDH1A1 | |
| SCHEMBL3722771 | 0.83 | MAOB (0.60) | NPC1MAPTMAOBALDH1A1HTT | |
| SCHEMBL12938497 | 0.83 | ALOX5 (0.78) | NPC1MAPTMRGPRX4MAOBALOX5 | |
| SCHEMBL18545979 | 0.82 | MAOB (0.60) | MAPTMRGPRX4MAOBALDH1A1HTT | |
| Acetic Acid SCHEMBL9428134 | 0.82 | SMN1; SMN2 (0.70) | NPC1MAPTMRGPRX4MAOBALDH1A1 | |
| SCHEMBL6520384 | 0.81 | NR4A2 (0.71) | NPC1MAPTMRGPRX4SMN1; SMN2RAB9A | |
| SCHEMBL18546031 | 0.81 | MRGPRX4 (0.69) | NPC1MAPTMRGPRX4SMN1; SMN2RAB9A | |
| SCHEMBL7791330 | 0.80 | RAB9A (0.62) | NPC1MAPTMRGPRX4MAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |