Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18786381 | 1.00 | EPHX1 (0.58) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL18786345 | 1.00 | EPHX1 (0.58) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL18547429 | 0.99 | EPHX1 (0.56) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL18583443 | 0.93 | EPHX1 (0.54) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL18583469 | 0.92 | EPHX1 (0.55) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL18583870 | 0.91 | TRPM8 (0.61) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL18547556 | 0.91 | TRPM8 (0.61) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL18583490 | 0.90 | EPHX1 (0.54) | EPHX1TRPM8TRPA1TRPV1 | |
| Hydrochloric Acid SCHEMBL18547896 | 0.90 | EPHX1 (0.54) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL18563060 | 0.89 | EPHX1 (0.52) | EPHX1TRPM8TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180312463-A1 | Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products | PROCTER & GAMBLE (US) | 2018-11-01 | — | — | US | disclosed |
| WO-2017070418-A1 | SYNTHESIS OF CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2017-04-27 | — | — | WO | disclosed |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | PROCTER & GAMBLE (US) | 2017-03-02 | — | — | US | disclosed |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | PROCTER & GAMBLE (US) | 2017-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312463-A1 | Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products | SRM, ACMSD, CUTA | EPHX1 4022/4885TRPM8 270/4885TRPA1 41/4885 |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | CUTA, ACMSD, SRM | EPHX1 4153/4885TRPM8 376/4885TRPA1 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.