Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5676562 | 0.87 | GPR52 (0.44) | TP53GPR52 | |
| SCHEMBL5795177 | 0.86 | CHRM2 (0.48) | HTR2AAOC3CHRM2HTR1AADRA2A | |
| SCHEMBL205556 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL8812500 | 0.85 | L3MBTL1 (0.48) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL5795176 | 0.84 | TP53 (0.44) | TP53ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL9248755 | 0.83 | SIGMAR1 (0.50) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL29274338 | 0.81 | TAAR1 (0.50) | TP53ALDH1A1HPGDTAAR1ATM | |
| SCHEMBL6471921 | 0.80 | SIGMAR1 (0.48) | TP53HPGDSMN1; SMN2CHRM2HTR1A | |
| SCHEMBL4831472 | 0.79 | GPR52 (0.48) | TP53ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL1071430 | 0.79 | GPR52 (0.48) | TP53ALDH1A1HPGDALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102008459-B | Antibacterial agents | BIOTA SCIENT MAN | 2013-05-29 | — | — | CN | claimed |
| EP-0586418-A1 | SUBSTITUTED TRIAZOLINONES | BAYER AG (DE) | 1994-03-16 | — | — | EP | claimed |
| US-5276008-A | Herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| WO-1992020663-A1 | SUBSTITUTED TRIAZOLINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-26 | — | — | WO | claimed |
| EP-0502307-A2 | Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones | BAYER AG (DE) | 1992-09-09 | — | — | EP | claimed |
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-111699186-B | C 2 -C 3 Alkenyl substituted ruimide dyes, curable silicone compositions and C 2 -C 3 Cured products of alkenyl substituted ruimide dyes | 巴斯夫欧洲公司 | 2024-03-05 | — | — | CN | disclosed |
| US-11685721-B2 | Human plasma kallikrein inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-11334695-B2 | Antiperspirant and deodorant compositions comprising malodor reduction compositions | THE PROCTER & GAMBLE COMPANY (US) | 2022-05-17 | — | — | US | disclosed |
| US-11334694-B2 | Personal care compositions comprising malodor reduction compositions | THE PROCTER & GAMBLE COMPANY (US) | 2022-05-17 | — | — | US | disclosed |
| CN-113307772-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-108191655-B | Synthetic method and application of American western corn rootworm sex pheromone | 西北农林科技大学 | 2021-05-28 | — | — | CN | disclosed |
| EP-0502307-A2 | Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones | BAYER AG (DE) | 1992-09-09 | — | — | EP | disclosed |
| EP-0500853-A1 | PHENYLETHANOLAMINES, DRUGS CONTAINING THESE COMPOUNDS, AND A METHOD OF PREPARING THEM. | THOMAE GMBH DR K (DE) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004316-A1 | PHENYLETHANOLAMINES, DRUGS CONTAINING THESE COMPOUNDS, AND A METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1992-03-19 | — | — | WO | disclosed |
| EP-0474391-A2 | Polyolefins | NIPPON OIL CO. LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |
| EP-0165437-B1 | PROCESS FOR THE PREPARATION OF SOLID POLYISOCYANATES HAVING A DELAYED REACTIVITY, DISPERSED POLYISOCYANATES ENVELOPED BY POLYMERS, AND THEIR USE | BAYER AG (DE) | 1988-09-21 | — | — | EP | disclosed |
| US-4268674-A | OXIME, AZODICARBOXYLATE, HYPOHALITE | THE DOW CHEMICAL COMPANY (US) | 1981-05-19 | — | — | US | disclosed |
| US-4254122-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF PROSTAGLANDIN SYNTHETASE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-03 | — | — | US | disclosed |
| US-3931218-A | HYPOGLYCEMIC ANTIRESERPINE, ANTIULCER, OGENIC, ANTIARRHYTHMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685721-B2 | Human plasma kallikrein inhibitors | KLKB1, KLK5, KLK1 | TP53 4560/4885ALDH1A1 1136/4885HPGD 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.