Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | STAT6 | P42226 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17147743 | 0.68 | CYP19A1 (0.56) | CYP19A1PKMALDH1A1LMNATP53 | |
| SCHEMBL2543370 | 0.65 | POLB (0.35) | ALDH1A1KMT2ARECQLTDP1 | |
| Dehydrocostuslactone SCHEMBL699070 | 0.65 | CYP19A1 (0.46) | CYP19A1PKMALDH1A1LMNATP53 | |
| Dehydrocostuslactone SCHEMBL31029489 | 0.65 | CYP19A1 (0.46) | CYP19A1PKMALDH1A1LMNATP53 | |
| Dehydrocostuslactone SCHEMBL936050 | 0.65 | CYP19A1 (0.46) | CYP19A1PKMALDH1A1LMNATP53 | |
| SCHEMBL8394084 | 0.64 | CYP19A1 (0.44) | CYP19A1PKMLMNATP53CYP3A4 | |
| SCHEMBL24299728 | 0.61 | CYP19A1 (0.41) | CYP19A1PKMLMNATP53CYP3A4 | |
| SCHEMBL10192292 | 0.61 | CYP19A1 (0.41) | CYP19A1PKMLMNATP53CYP3A4 | |
| Dehydrozaluzanin C SCHEMBL17214360 | 0.61 | CYP19A1 (0.42) | CYP19A1PKMALDH1A1LMNATP53 | |
| SCHEMBL18981060 | 0.59 | CYP19A1 (0.40) | CYP19A1PKMLMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170049793-A1 | MOLECULAR ACTIVATORS OF THE WNT/BETA-CATENIN PATHWAY | THE GENERAL HOSPITAL CORPORATION (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049793-A1 | MOLECULAR ACTIVATORS OF THE WNT/BETA-CATENIN PATHWAY | WNT1, CTNNB1, WNT3A | CYP19A1 2019/4885PKM 3877/4885ALDH1A1 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.