Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | HPGD | P15428 | 8/20 | 1.00 |
| ▸ | GAA | P10253 | 7/20 | 1.00 |
| ▸ | GLA | P06280 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | THRB | P10828 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12722310 | 0.85 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL18550800 | 0.83 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL18550801 | 0.82 | GAA (0.71) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL18550854 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL1626916 | 0.81 | KMT2A (1.00) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL27225472 | 0.81 | LMNA (0.79) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL5266910 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL27225557 | 0.76 | KDM4E (0.61) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL3956317 | 0.75 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL14158306 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11576892-B2 | Benzopyran derivatives and uses thereof | NOVATION PHARMACEUTICALS INC. (CA) | 2023-02-14 | — | — | US | disclosed |
| US-20220016071-A1 | BENZOPYRAN DERIVATIVES AND USES THEREOF | NOVATION PHARMACEUTICALS INC. (CA) | 2022-01-20 | — | — | US | disclosed |
| WO-2017027973-A1 | BENZOPYRAN DERIVATIVES AND USES THEREOF | NOVATION PHARMACEUTICALS INC. (CA) | 2017-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016071-A1 | BENZOPYRAN DERIVATIVES AND USES THEREOF | UPF1, EIF2AK2, RPL37A | ALDH1A1 1232/4885KDM4E 4147/4885HPGD 420/4885 |
| US-11576892-B2 | Benzopyran derivatives and uses thereof | UPF1, EIF2AK2, RPL37A | ALDH1A1 1232/4885KDM4E 4147/4885HPGD 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.