Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161622 | 0.86 | ALOX15 (0.53) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5322100 | 0.85 | PRNP (0.44) | PRNPALOX15ALDH1A1FABP4KDM4E | |
| SCHEMBL28064460 | 0.84 | ALOX15 (0.52) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19950528 | 0.81 | TAS2R14 (0.46) | PRNPALOX15ALDH1A1FABP4KDM4E | |
| SCHEMBL30070392 | 0.81 | TAS2R14 (0.46) | PRNPALOX15ALDH1A1FABP4KDM4E | |
| SCHEMBL29393947 | 0.80 | SLC7A5 (0.42) | ALDH1A1KDM4EHPGDKMT2ATSHR | |
| Terephthalic Acid SCHEMBL11573174 | 0.78 | SRD5A2 (0.50) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29678146 | 0.78 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL273494 | 0.78 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8849607 | 0.78 | ALDH1A1 (0.54) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023057548-A1 | CCR6 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-04-13 | — | — | WO | disclosed |
| WO-2023049438-A1 | GRK2 INHIBITORS AND USES THEREOF | SONATA THERAPEUTICS, INC. (US) | 2023-03-30 | — | — | WO | disclosed |
| WO-2023022234-A1 | HUMAN TRANSFERRIN RECEPTOR–BINDING PEPTIDE | ペプチドリーム株式会社 | 2023-02-23 | — | — | WO | disclosed |
| CN-114044905-B | Preparation method of end-group functionalized polydimethylsiloxane | 复旦大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-114044905-A | Preparation method of end group functionalized polydimethylsiloxane | 复旦大学 | 2022-02-15 | — | — | CN | disclosed |
| EP-1470102-B1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | MERCK SERONO SA (CH) | 2011-05-25 | — | — | EP | disclosed |
| US-7592477-B2 | Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (PTPs) | LABORATOIRES SERONO SA (CH) | 2009-09-22 | — | — | US | disclosed |
| US-7399504-B2 | Method of preparing an insoluble polymer film on a substrate from a soluble polymer containing labile solubilizing groups | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-07-15 | — | — | US | disclosed |
| US-20050124656-A1 | Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases(ptps) | APPLIED RESEARCH SYSTEMS ARS (NL) | 2005-06-09 | — | — | US | disclosed |
| US-20050106324-A1 | Method of preparing an insoluble polymer film on a substrate from a soluble polymer containing labile solubilizing groups | DOW GLOBAL TECHNOLOGIES LLC | 2005-05-19 | — | — | US | disclosed |
| WO-2005036666-A2 | METHOD OF PREPARING AN INSOLUBLE POLYMER FILM ON A SUBSTRATE FROM A SOLUBLE POLYMER CONTAINING LABILE SOLUBILIZING GROUPS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-04-21 | — | — | WO | disclosed |
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124656-A1 | Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases(ptps) | PTPRS, PTPA, PTPMT1 | PRNP 4748/4885ALOX15 2503/4885ALDH1A1 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.