Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855103 | 0.85 | PRNP (0.46) | PRNPALOX15ALDH1A1FABP4KDM4E | |
| SCHEMBL30070392 | 0.78 | TAS2R14 (0.46) | PRNPALOX15ALDH1A1FABP4KDM4E | |
| SCHEMBL19950528 | 0.78 | TAS2R14 (0.46) | PRNPALOX15ALDH1A1FABP4KDM4E | |
| SCHEMBL161622 | 0.74 | ALOX15 (0.53) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10707667 | 0.72 | ALOX15 (0.52) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28064460 | 0.72 | ALOX15 (0.52) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5081336 | 0.72 | ALDH1A1 (0.50) | PRNPALOX15ALDH1A1FABP4KDM4E | |
| SCHEMBL5322102 | 0.71 | PRNP (0.37) | PRNPALOX15HPGDCA12CA1 | |
| SCHEMBL31189227 | 0.71 | PRNP (0.37) | PRNPALOX15HPGDCA12CA1 | |
| SCHEMBL29621571 | 0.71 | TSHR (0.52) | PRNPALOX15ALDH1A1FABP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117289-A2 | METHODS FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION OR URINARY INCONTINENCE | INOTEK PHARMACEUTICALS CORPORATION (US) | 2007-10-18 | — | — | WO | disclosed |
| EP-1603567-A4 | TETRACYCLIC BENZAMIDE DERIVATIVES AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORP (US) | 2006-10-18 | — | — | EP | disclosed |
| EP-1603567-A2 | TETRACYCLIC BENZAMIDE DERIVATIVES AND METHODS OF USE THEREOF | Inotek Pharmaceuticals Corporation (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2005009398-A2 | TETRACYCLIC BENZAMIDE DERIVATIVES AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2005-02-03 | — | — | WO | disclosed |