SCHEMBL18554121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4340073	0.91	TNF (0.50)	TNFHTTPOLBL3MBTL1KDM4E
	SCHEMBL643777	0.91	TNF (0.50)	TNFHTTPOLBL3MBTL1KDM4E
	SCHEMBL29620246	0.89	HTT (0.52)	HTTPOLBL3MBTL1KDM4ELMNA
	SCHEMBL2468068	0.89	HTT (0.52)	HTTPOLBL3MBTL1KDM4ELMNA
	SCHEMBL14331200	0.87	TNF (0.52)	TNFHTTPOLBL3MBTL1KDM4E
	SCHEMBL20631194	0.86	HTT (0.51)	HTTPOLBLMNANPC1CYP3A4
	SCHEMBL16067368	0.86	HTT (0.51)	HTTPOLBL3MBTL1LMNACASP3
	SCHEMBL12221992	0.85	HTT (0.47)	HTTPOLBL3MBTL1KDM4ELMNA
	SCHEMBL1742989	0.85	POLB (0.47)	HTTPOLBL3MBTL1KDM4ELMNA
	SCHEMBL32690852	0.85	HTT (0.50)	TNFHTTPOLBKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.