Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | MME | P08473 | 6/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 5/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18576790 | 1.00 | FFAR1 (0.51) | FFAR1MMEFAAHMGLLCPA3 | |
| SCHEMBL18554244 | 0.85 | POLB (0.56) | FFAR1MMECPA3MMEL1MEN1 | |
| SCHEMBL18554169 | 0.85 | POLB (0.56) | FFAR1MMECPA3MMEL1MEN1 | |
| SCHEMBL18576791 | 0.84 | MMEL1 (0.43) | MMEFAAHMGLLMMEL1MEN1 | |
| SCHEMBL18576792 | 0.84 | MMEL1 (0.43) | MMEFAAHMGLLMMEL1MEN1 | |
| SCHEMBL28632027 | 0.78 | MME (0.54) | MMEMMEL1ACE | |
| SCHEMBL28632025 | 0.78 | MME (0.54) | MMEMMEL1ACE | |
| SCHEMBL18554256 | 0.76 | PPARG (0.44) | MMEFAAHMGLLMEN1KMT2A | |
| SCHEMBL11480552 | 0.75 | ALDH1A1 (0.61) | CPA3MEN1KMT2ALMNAGAA | |
| SCHEMBL30300760 | 0.74 | MME (0.41) | MMEFAAHMGLLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017033128-A1 | BIPHENYL-SUBSTITUED 4-AMINO-BUTYRIC ACID DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF NEP INHIBITORS | NOVARTIS AG (CH) | 2017-03-02 | — | — | WO | disclosed |
| WO-2017033128-A1 | BIPHENYL-SUBSTITUED 4-AMINO-BUTYRIC ACID DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF NEP INHIBITORS | NOVARTIS AG (CH) | 2017-03-02 | — | — | WO | disclosed |