Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.41 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18576792 | 1.00 | MMEL1 (0.43) | MMEL1PTPN1GSK3AGSK3BSRR | |
| SCHEMBL20072199 | 0.87 | ALDH1A1 (0.43) | MMEL1PTPN1SRRPSAT1ATM | |
| SCHEMBL18554190 | 0.84 | FFAR1 (0.51) | MMEL1HTTMEN1KMT2AMME | |
| SCHEMBL18576790 | 0.84 | FFAR1 (0.51) | MMEL1HTTMEN1KMT2AMME | |
| SCHEMBL30300760 | 0.81 | MME (0.41) | MMEFAAHMGLL | |
| SCHEMBL597533 | 0.78 | SRR (0.50) | MMEL1PTPN1SRRPSAT1ATM | |
| SCHEMBL1908571 | 0.78 | SRR (0.50) | MMEL1PTPN1SRRPSAT1ATM | |
| Hydrochloric Acid SCHEMBL597532 | 0.77 | SRR (0.51) | MMEL1PTPN1SRRPSAT1ATM | |
| Hydrochloric Acid SCHEMBL597534 | 0.77 | SRR (0.51) | MMEL1PTPN1SRRPSAT1ATM | |
| SCHEMBL18554256 | 0.75 | PPARG (0.44) | MEN1KMT2AMMECYP1A2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017033128-A1 | BIPHENYL-SUBSTITUED 4-AMINO-BUTYRIC ACID DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF NEP INHIBITORS | NOVARTIS AG (CH) | 2017-03-02 | — | — | WO | disclosed |