Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 12/20 | 0.43 |
| ▸ | ACE | P12821 | 12/20 | 0.43 |
| ▸ | CPA1 | P15085 | 3/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632025 | 0.85 | MME (0.54) | MMEACE | |
| SCHEMBL28632027 | 0.85 | MME (0.54) | MMEACE | |
| SCHEMBL30300760 | 0.80 | MME (0.41) | MMEACEFAAHMGLL | |
| SCHEMBL18554190 | 0.76 | FFAR1 (0.51) | MMEACEMEN1KMT2AFAAH | |
| SCHEMBL18576790 | 0.76 | FFAR1 (0.51) | MMEACEMEN1KMT2AFAAH | |
| SCHEMBL18576792 | 0.75 | MMEL1 (0.43) | MMEMEN1KMT2ACYP1A2FAAH | |
| SCHEMBL18576791 | 0.75 | MMEL1 (0.43) | MMEMEN1KMT2ACYP1A2FAAH | |
| SCHEMBL28389111 | 0.71 | MME (0.53) | MMEACE | |
| SCHEMBL28412302 | 0.71 | MME (0.53) | MMEACE | |
| SCHEMBL16980961 | 0.69 | MMP12 (0.55) | PPARGPPARAPPARDMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017033128-A1 | BIPHENYL-SUBSTITUED 4-AMINO-BUTYRIC ACID DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF NEP INHIBITORS | NOVARTIS AG (CH) | 2017-03-02 | — | — | WO | disclosed |