Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18555678 | 1.00 | PTGER1 (0.41) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL18555187 | 0.92 | KMT2A (0.43) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL18555186 | 0.92 | KMT2A (0.43) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL17345581 | 0.86 | PAM (0.47) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL17867043 | 0.83 | ALDH1A1 (0.46) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL17867041 | 0.83 | ALDH1A1 (0.46) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL29634735 | 0.83 | ALDH1A1 (0.46) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL29962896 | 0.83 | ALDH1A1 (0.46) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL18555493 | 0.76 | PTGER3 (0.52) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL18555490 | 0.76 | PTGER3 (0.52) | PTGER1PTGER4PTGER3PTGER2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035288-A1 | COMPOSITION AND METHOD FOR PREVENTION, MITIGATION OR TREATMENT OF AN ENTEROPATHOGENIC BACTERIAL INFECTION | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2017-03-02 | — | — | WO | disclosed |