Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17867043 | 1.00 | ALDH1A1 (0.46) | ALDH1A1FFAR1MAPTCYP19A1RXRA | |
| SCHEMBL17867041 | 1.00 | ALDH1A1 (0.46) | ALDH1A1FFAR1MAPTCYP19A1RXRA | |
| SCHEMBL29962896 | 1.00 | ALDH1A1 (0.46) | ALDH1A1FFAR1MAPTCYP19A1RXRA | |
| SCHEMBL1793023 | 0.84 | ALDH1A1 (0.42) | ALDH1A1CYSLTR2CYSLTR1PTGER1PTGER4 | |
| SCHEMBL18555680 | 0.83 | PTGER1 (0.41) | ALDH1A1FFAR1MAPTCYP19A1RXRA | |
| SCHEMBL18555678 | 0.83 | PTGER1 (0.41) | ALDH1A1FFAR1MAPTCYP19A1RXRA | |
| SCHEMBL9574440 | 0.81 | NFKB1 (0.55) | ALDH1A1FFAR1MAPTCYP19A1RXRA | |
| SCHEMBL18112877 | 0.79 | GRIK1 (0.50) | ALDH1A1FFAR1MAPTCYP19A1RXRA | |
| SCHEMBL18112878 | 0.79 | GRIK1 (0.50) | ALDH1A1FFAR1MAPTCYP19A1RXRA | |
| SCHEMBL3993752 | 0.79 | NFE2L2 (0.58) | ALDH1A1MAPTKDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111807952-B | Novel compound participating in lipid metabolism and preparation method thereof | 中国医学科学院医药生物技术研究所 | 2022-06-03 | — | — | CN | disclosed |